Zobrazeno 1 - 10
of 35
pro vyhledávání: '"R M Maiorino"'
Publikováno v:
Acta Pharmacologica et Toxicologica. 59:467-470
Autor:
H. Vasken Aposhian, Gerald F. O'Malley, R M Maiorino, Mingsheng Ma, Richard C. Dart, Wayne A. Van Voorhies, Robert A. Zakharyan, Luke Yip, William R. Cullen, Paul Andrewes, Baoshan Zheng, Allison Titcomb, Mariano E. Cebrián, Sheila M. Healy, Mary M. Aposhian, X. Chris Le, Zhai Cheng
Publikováno v:
Toxicology and Applied Pharmacology. 165:74-83
The administration of sodium 2,3-dimercapto-1-propane sulfonate (DMPS) to humans chronically exposed to inorganic arsenic in their drinking water resulted in the increased urinary excretion of arsenic, the appearance and identification of monomethyla
Publikováno v:
Toxicology. 109:49-55
Since there has been concern about whether any of the chelating agents used therapeutically might cause an initial redistribution of heavy metals to the brain and since the sodium salt of 2,3-dimercapto-1-propanesulfonic acid (Dimaval, DMPS) has been
Autor:
Zhao-Fa Xu, Diego Gonzalez-Ramirez, H. Vasken Aposhian, Katherine M. Hurlbut, Miguel Angel Zúñiga-Charles, Mary M. Aposhian, Pablo Junco-Munoz, R M Maiorino, Richard C. Dart
Publikováno v:
Toxicology. 97:23-38
Four chelating agents that have been used most commonly for the treatment of humans intoxicated with lead, mercury, arsenic or other heavy metals and metalloids are reviewed as to their advantages, disadvantages, metabolism and specificity. Of these,
Publikováno v:
Fundamental and Applied Toxicology. 14:598-607
N-(2,3-Dimercaptopropyl) phthalamidic acid (DMPA), meso-dimercaptosuccinic acid (DMSA), and 2,3-dimercapto-1-propanesulfonic acid (DMPS) are dithiol chelating agents with antidotal activity for lead, mercury, arsenic, and other heavy metals. The bili
Publikováno v:
Journal of toxicology. Clinical toxicology. 41(4)
Some medical practitioners prescribe GSH and vitamin C alone or in combination with DMPS or DMSA for patients with mercury exposure that is primarily due to the mercury vapor emitted by dental amalgams. Hypothesis. This study tested the hypothesis th
Autor:
H V, Aposhian, B, Zheng, M M, Aposhian, X C, Le, M E, Cebrian, W, Cullen, R A, Zakharyan, M, Ma, R C, Dart, Z, Cheng, P, Andrewes, L, Yip, G F, O'Malley, R M, Maiorino, W, Van Voorhies, S M, Healy, A, Titcomb
Publikováno v:
Toxicology and applied pharmacology. 165(1)
The administration of sodium 2,3-dimercapto-1-propane sulfonate (DMPS) to humans chronically exposed to inorganic arsenic in their drinking water resulted in the increased urinary excretion of arsenic, the appearance and identification of monomethyla
Autor:
R M, Maiorino, D, Gonzalez-Ramirez, M, Zuniga-Charles, Z, Xu, K M, Hurlbut, M M, Aposhian, R C, Dart, J S, Woods, P, Ostrosky-Wegman, M E, Gonsebatt, H V, Aposhian
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(2)
The sodium salt of 2,3-dimercaptopropane-1-sulfonic acid (Dimaval; DMPS) challenge test has been given previously to humans exposed to elemental mercury (vapor) or mercuric salts, but not mercurous salts. The test (300 mg p.o., after an 11-hr fast) w
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(1)
The binding of 2,3-dimercapto-1-propanesulfonate (DMPS) in plasma was determined in three healthy young adults after a single 300-mg p.o. dose. By 5 hr after DMPS administration, 62.5% of the total plasma DMPS was bound to proteins. The remainder con
Autor:
D, Gonzalez-Ramirez, R M, Maiorino, M, Zuniga-Charles, Z, Xu, K M, Hurlbut, P, Junco-Munoz, M M, Aposhian, R C, Dart, J H, Diaz Gama, D, Echeverria
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 272(1)
The sodium salt of 2,3-dimercaptopropane-1-sulfonic acid (DMPS) challenge test (300 mg p.o. after an 11-hr fast) was given in Monterrey, Mexico to dental and nondental personnel. Urine samples were collected and analyzed for total mercury. The mean m