Zobrazeno 1 - 6
of 6
pro vyhledávání: '"R M L Jones"'
Autor:
Robin E. Offord, Egeli R, Keith Rose, André Pèlegrin, A Donath, Jean-Etienne Ryser, A Smith, R M L Jones
Publikováno v:
Nuclear medicine and biology. 25(3)
To circumvent radionuclide accumulation in nontarget tissues when employing metallic radionuclides for radioimmunoscintigraphy or radioimmunotherapy, we have investigated the effect of the chelating agent deferroxamine (DFO) on the biodistribution of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3fcb3676984d5fce40377ed71d5b41c
https://pubmed.ncbi.nlm.nih.gov/9620632
https://pubmed.ncbi.nlm.nih.gov/9620632
Publikováno v:
Bioconjugate chemistry. 2(3)
A two-step approach to the production of well-defined protein conjugates is described. In the first step, a linker group, carbohydrazide, having unique reactivity (a hydrazide group) is attached specifically to the carboxyl terminus by using enzyme-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa65c4ed5b59bb4396ff842eccf2c30
https://pubmed.ncbi.nlm.nih.gov/1932214
https://pubmed.ncbi.nlm.nih.gov/1932214
Publikováno v:
Peptides 1990 ISBN: 9789072199089
Peptides 1990
Peptides 1990
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd28aa03008acf6ec1b369578bc4e4c5
https://doi.org/10.1007/978-94-011-3034-9_338
https://doi.org/10.1007/978-94-011-3034-9_338
Publikováno v:
Biochemical Journal. 247:785-788
Biosynthetic human proinsulin (obtained by recombinant DNA techniques) was used as the starting material for the preparation, by semisynthetic methods, of [3H]proinsulin with the label at the N-terminal phenylalanine residue. The labelled proinsulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82d0b33d633ea56deef1916ad202a9a
https://doi.org/10.1042/bj2470785
https://doi.org/10.1042/bj2470785
Autor:
Robin Ewart Offord, Luc-Alain Savoy, Keith Rose, R M L Jones, J G Davies, A V Muir, S. Pochon
Publikováno v:
The Biochemical journal. 249(1)
We describe the isolation by reversed-phase h.p.l.c. of a number of products of the degradation of insulin by insulin proteinase and their direct analysis by fast atom bombardment mass spectrometry (f.a.b.-m.s.). Various semisynthetically labelled in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dd1470be66132660138c9d5e7a19010
https://pubmed.ncbi.nlm.nih.gov/3277618
https://pubmed.ncbi.nlm.nih.gov/3277618
Autor:
R M L Jones, R E Offord
Publikováno v:
The Biochemical journal. 203(1)
1. We report the trypsin-catalysed conversion, in high yield, of peptides to peptide hydrazides, t-butyloxycarbonylhydrazides and phenylhydrazides. The substitution is at the alpha-carboxy group. 2. We discuss the relative merits of carrying out the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd551be3379f6df1476f2d6a85e74b4c
https://pubmed.ncbi.nlm.nih.gov/6808990
https://pubmed.ncbi.nlm.nih.gov/6808990