Zobrazeno 1 - 10
of 267
pro vyhledávání: '"R M Khomutov"'
Autor:
Alexey A. Belogurov, Spyros D. Chatziefthimiou, E. N. Hurs, R. M. Khomutov, Alexander Zlobin, Ivan V. Smirnov, Alexander G. Gabibov, G.M. Blackburn, V. D. Knorre, Matthias Wilmanns, Natalia A. Ponomarenko, A. V. Stepanova, A. O. Zalevskiy, Andrey V. Golovin
Publikováno v:
Doklady Biochemistry and Biophysics. 475:245-249
It is proposed to perform quantum mechanical/molecular dynamics calculations of chemical reactions that are planned to be catalyzed by antibodies and then conduct a virtual screening of the library of potential antibody mutants to select an optimal b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a0007fc8ad295f9ca388e7469951355
https://doi.org/10.1134/s1607672917040019
https://doi.org/10.1134/s1607672917040019
Autor:
E. N. Khurs, O. D. Mikituk, V. G. Dzhavakhiya, T. A. Nazarova, L. A. Shcherbakova, T. I. Osipova, R. M. Khomutov, N. S. Zhemchuzhina
Publikováno v:
Doklady Biochemistry and Biophysics. 461:69-71
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b6c4f2fff677b5c63e3c4201e7acfb
https://doi.org/10.1134/s1607672915020015
https://doi.org/10.1134/s1607672915020015
Autor:
R. M. Khomutov
Publikováno v:
Biochemistry (Moscow). 67:1085-1088
Modern approaches for developing antibodies with coenzyme-dependent activities are discussed for pyridoxal 5"-phosphate dependent transformation of amino acid as an example. A new type of antigens analogous to enzyme–substrate compounds is suggeste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b49fa24cb82e6e4da8c4b8fb6d7fbff1
https://doi.org/10.1023/a:1020955005503
https://doi.org/10.1023/a:1020955005503
Autor:
Elena N. Khurs, R. M. Khomutov, Tatyana V. Demidkina, Yurii N. Zhukov, Olga Gogoleva, Bazhulina Np, Maria V. Barbolina, N. G. Faleev, Vassili M. Belikov
Publikováno v:
European Journal of Biochemistry. 267:6897-6902
The phosphinic analogues of tyrosine and pyruvate were first demonstrated to be substrates in the reactions of elimination and synthesis catalyzed by tyrosine phenol-lyase. Kinetic parameters of the enzymatic process were determined, and the first en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c82ac1dce96c9eb4f359d6ad4f44057b
https://doi.org/10.1046/j.1432-1033.2000.01794.x
https://doi.org/10.1046/j.1432-1033.2000.01794.x
Publikováno v:
Russian Chemical Bulletin. 48:1348-1351
Phosphinic analogs of the key compounds of the metabolism of methionine were synthesized. The compounds obtained were selectively oxidized either at the phosphinic group or at the sulfur-containing fragment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ace5053fb89a4a1b7829befd71204a31
https://doi.org/10.1007/bf02495302
https://doi.org/10.1007/bf02495302
Crystal Structures and Solution Studies of Oxime Adducts of Mitochondrial Aspartate Aminotransferase
Autor:
Marat Ya. Karpeisky, Alex R. Khomutov, Erika Sandmeier, Tilman Schirmer, Johan N. Jansonius, R. M. Khomutov, Zora Marković-Housley, Philipp Christen, Erhard Hohenester
Publikováno v:
European Journal of Biochemistry. 236:1025-1032
The interaction of mitochondrial aspartate aminotransferase with hydroxylamine and five derivatives (in which the hydroxyl hydrogen is replaced by the side chain of naturally occurring amino acids) was investigated by X-ray diffraction as well as by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a345ba3c20fe9e294c239288902af610
https://doi.org/10.1111/j.1432-1033.1996.01025.x
https://doi.org/10.1111/j.1432-1033.1996.01025.x
Autor:
N. A. Vavilova, Yu. N. Zhukov, Tatyana I. Osipova, V. G. Dzhavakhia, E. N. Khurs, R. M. Khomutov, T. M. Voinova
Publikováno v:
Doklady Biochemistry and Biophysics. 397:210-212
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a53f37f8b7cc35f0ba278f8fb25084
https://doi.org/10.1023/b:dobi.0000039465.65071.6e
https://doi.org/10.1023/b:dobi.0000039465.65071.6e
Autor:
E. A. Morozova, R. M. Khomutov, L.N. Zakomirdina, Alexey D. Nikulin, Tatyana V. Demidkina, S.V. Revtovich, E. N. Khurs
Publikováno v:
Biochemistry. Biokhimiia. 76(5)
Crystal structures of Citrobacter freundii methionine γ-lyase complexes with the substrates of γ- (L-1-amino-3-methylthiopropylphosphinic acid) and β- (S-ethyl-L-cysteine) elimination reactions and the competitive inhibitor L-norleucine have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b92db92e692960cf77c7483f17c8a5f
https://pubmed.ncbi.nlm.nih.gov/21639836
https://pubmed.ncbi.nlm.nih.gov/21639836
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f354464b37e7e6c2d051cc25716ecb5a
https://doi.org/10.1002/chin.199709178
https://doi.org/10.1002/chin.199709178
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc46a4bf0e022ceefc0ac82c5f8a112c
https://doi.org/10.1002/chin.199730154
https://doi.org/10.1002/chin.199730154