Zobrazeno 1 - 7
of 7
pro vyhledávání: '"R M Hudziak"'
Autor:
M S, Tai, J E, McCartney, G P, Adams, D, Jin, R M, Hudziak, H, Oppermann, A A, Laminet, M A, Bookman, E J, Wolf, S, Liu
Publikováno v:
Cancer research. 55
Single-chain Fv proteins containing a COOH-terminal cysteine (sFv') were constructed by using an antidigoxin 26.10 sFv and an anti-c-erbB-2 741F8 sFv. The fully active sFv' proteins were prepared by expression in Escherichia coli as insoluble inclusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e983a758fc8e13e9dff312237efdd7fc
https://pubmed.ncbi.nlm.nih.gov/7493381
https://pubmed.ncbi.nlm.nih.gov/7493381
Autor:
J E, McCartney, M S, Tai, R M, Hudziak, G P, Adams, L M, Weiner, D, Jin, W F, Stafford, S, Liu, M A, Bookman, A A, Laminet
Publikováno v:
Protein engineering. 8(3)
Single-chain Fv fusions with C-terminal cysteinyl peptides (sFv') have been engineered using model sFv proteins based upon the 26-10 anti-digoxin IgG and 741F8 anti-c-erbB-2 IgG monoclonal antibodies. As part of the 741F8 sFv construction process, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47bbe486436e833fbf852c1e8d0b85ad
https://pubmed.ncbi.nlm.nih.gov/7479692
https://pubmed.ncbi.nlm.nih.gov/7479692
Autor:
R M, Hudziak, A, Ullrich
Publikováno v:
The Journal of biological chemistry. 266(35)
The HER2 (c-erbB-2) gene encodes a protein, p185HER2, which possesses all of the structural characteristics and functional properties of a growth factor receptor, although its ligand has not yet been well characterized. HER2 is the human homolog of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1512e1349303a4d3c4870ce8400c4936
https://pubmed.ncbi.nlm.nih.gov/1684181
https://pubmed.ncbi.nlm.nih.gov/1684181
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 1(3)
Alterations in the structure and expression of protein tyrosine kinases are associated with cellular transformation and tumorigenicity. These enzymes may contribute to tumor progression by interfering with host mechanisms of antitumor surveillance. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c4a3039f673375367c08264f1ab480d
https://pubmed.ncbi.nlm.nih.gov/2078501
https://pubmed.ncbi.nlm.nih.gov/2078501
Publikováno v:
Cancer research. 50(5)
High levels of expression of either the epidermal growth factor receptor or the receptor-like HER2/neu gene product p185HER2 have been observed in a variety of human malignancies. Because of the association of this high level expression with certain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66f0abc89cd5794f6fd7afeeeb4ccbf3
https://pubmed.ncbi.nlm.nih.gov/1689212
https://pubmed.ncbi.nlm.nih.gov/1689212
Publikováno v:
Molecular and Cellular Biology. 9:1165-1172
The HER2/c-erbB-2 gene encodes the epidermal growth factor receptorlike human homolog of the rat neu oncogene. Amplification of this gene in primary breast carcinomas has been show to correlate with poor clinical prognosis for certain cancer patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5775040ec964d469b14a3e21d16434e3
https://doi.org/10.1128/mcb.9.3.1165
https://doi.org/10.1128/mcb.9.3.1165
Autor:
R M Hudziak, Peter Palese, Mario R. Capecchi, G P Norton, Phillip A. Sharp, Ramamoorthy Belagaje, Frank A. Laski, Uttam L. RajBhandary
Publikováno v:
Scopus-Elsevier
We have used site-specific mutagenesis to change the anticodon of a Xenopus laevis tyrosine tRNA gene so that it would recognize ochre codons. This tRNA gene is expressed when amplified in monkey cells as part of a SV40 recombinant and efficiently su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7b9a69f31225c9f08b1c5784981d33
https://doi.org/10.1002/j.1460-2075.1984.tb02154.x
https://doi.org/10.1002/j.1460-2075.1984.tb02154.x