Zobrazeno 1 - 7
of 7
pro vyhledávání: '"R M Emanuele"'
Publikováno v:
International Journal of Cancer. 62:436-442
Some well-known fatty acid ester surfactants, e.g., Cremophor EL and Solutol HS 15, are modulators of multidrug resistance in vitro and in vivo. Because they are polydisperse, and their active component(s) have not been identified, the therapeutic po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d275c253738b2e0cb147e8e8b6056c
https://doi.org/10.1002/ijc.2910620413
https://doi.org/10.1002/ijc.2910620413
Autor:
P G, Komarov, A A, Shtil, L E, Buckingham, M, Balasubramanian, O, Piraner, R M, Emanuele, I B, Roninson, J S, Coon
Publikováno v:
International journal of cancer. 68(2)
Fatty acid ester surfactants Cremophor EL and Solutol HS 15 were described earlier as modulators of multidrug resistance mediated by MDR1 P-glycoprotein (Pgp). We have shown that the most active components of these polydisperse surfactants are fatty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0269653239494e56ce7d1c84b9c58f78
https://pubmed.ncbi.nlm.nih.gov/8900436
https://pubmed.ncbi.nlm.nih.gov/8900436
Autor:
L E, Buckingham, M, Balasubramanian, A R, Safa, H, Shah, P, Komarov, R M, Emanuele, J S, Coon
Publikováno v:
International journal of cancer. 65(1)
Fatty acid ester surfactants, e.g., Cremophor EL and Solutol HS 15, that modulate multi-drug resistance (MDR) have been described; however, the drug potential of these preparations is unclear because of the molecular heterogeneity of these and other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b153eeb3ea218212c7b4536652142b31
https://pubmed.ncbi.nlm.nih.gov/8543400
https://pubmed.ncbi.nlm.nih.gov/8543400
Publikováno v:
Anti-Cancer Drugs. 5:29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae9ba89f57696aef259b8d71d0fa1399
https://doi.org/10.1097/00001813-199409001-00067
https://doi.org/10.1097/00001813-199409001-00067
Publikováno v:
Nouvelle revue francaise d'hematologie. 26(4)
During the last few years many reports on the antithrombotic actions of low molecular weight fractions (LMF) have become available and are being tested in the experimental and clinical settings. Although derived from commercial heparins, the mode of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95dba6707dffeb23ef9d1a27a075776b
https://pubmed.ncbi.nlm.nih.gov/6473096
https://pubmed.ncbi.nlm.nih.gov/6473096
Publikováno v:
XIth International Congress on Thrombosis and Haemostasis.
Five different molecular weight (M. W.) fractions of heparin (M. W.'s 23,000 ; 17,450 ; 13,300 ; 9,000 and 5,100) were prepared by gel-filtration. Screening of these fractions in global and amidolytic assaysat a concentration of 2.5 ug/ml revealed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f95839c79d554b99a31f4c430bf55433
https://doi.org/10.1055/s-0038-1644178
https://doi.org/10.1055/s-0038-1644178
Autor:
R M Emanuele, J Fareed
Publikováno v:
XIth International Congress on Thrombosis and Haemostasis.
Three fractions of different molecular weight (M. W.) were obtained from gel-filtration of porcine mucosal heparin. These fractions along with unfractionated and a low M. W. heparin (CY 216) were compared for relative bioavailability in primates (Mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acb5693df62f146f8daef472325ffa85
https://doi.org/10.1055/s-0038-1644179
https://doi.org/10.1055/s-0038-1644179