Výsledky vyhledávání

Selectin haplotypes and the risk of venous thrombosis: influence of linkage disequilibrium with the factor V Leiden mutation

Autor: F. R. Rosendaal, R M Bertina, S. Uitte De Willige, M. de Visser, H. L. Vos, Jeanine J. Houwing-Duistermaat

Publikováno v: Journal of Thrombosis and Haemostasis. 6:478-485

Summary. Background: Selectins (E-, L- and P-selectin) and their most important counter-receptor P-selectin glycoprotein ligand (SELPLG) facilitate the interaction of platelets, leukocytes and endothelial cells at inflammatory sites. Selectin polymor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f56182c81076bef40e971a35837872
https://doi.org/10.1111/j.1538-7836.2007.02879.x

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Different effects of oral contraceptives containing different progestogens on protein S and tissue factor pathway inhibitor

Autor: F. R. Rosendaal, Anders E.A. Dahm, H. A. A. M. Van Vliet, R M Bertina, Frans M. Helmerhorst, P. Morten Sandset, Jan Rosing

Publikováno v: Journal of Thrombosis and Haemostasis. 6:346-351

Summary. Background: Oral contraceptives (OC) containing different types of progestogens induce different sensitivities to activated protein C (APC) measured with the thrombin generation-based APC-resistance test. These differences in APC resistance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1319047ecb943aa08611006bcd4d78
https://doi.org/10.1111/j.1538-7836.2008.02863.x

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Microparticle‐associated tissue factor activity: a link between cancer and thrombosis?

Autor: R M Bertina, Fred P.H.T.M. Romijn, I. K. Van Der Linden, Susanne Osanto, F. A. Prins, M. E. T. Tesselaar

Publikováno v: Journal of Thrombosis and Haemostasis. 5:520-527

Summary. Background: Cancer, in particular mucinous adenocarcinoma, is associated with venous thromboembolism (VTE). Tissue factor (TF), initiator of coagulation, plays a central role in the paradigm that clotting and tumor growth form a vicious circ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fb71965cfc3853e727c31d114a6b8c
https://doi.org/10.1111/j.1538-7836.2007.02369.x

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von Willebrand factor and its propeptide: the influence of secretion and clearance on protein levels and the risk of venous thrombosis

Autor: N H van Tilburg, V. Van Marion, F. R. Rosendaal, H. C. J. Eikenboom, R M Bertina, J. A. Van Mourik, Anne Yaël Nossent

Publikováno v: Journal of Thrombosis and Haemostasis. 4:2556-2562

Summary. Background and objectives: Elevated levels of factor (F)VIII are associated with an increased risk of thrombosis. FVIII levels are determined mainly by von Willebrand factor (VWF). We have investigated the contribution of secretion and clear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c08a2a48a67d3e3d2744365d8e386216
https://doi.org/10.1111/j.1538-7836.2006.02273.x

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Association between thrombin activatable fibrinolysis inhibitor genotype and levels in plasma: comparison of different assays

Autor: H. L. Vos, Dingeman C. Rijken, R M Bertina, A. H. C. Guimarães, N H van Tilburg

Publikováno v: British Journal of Haematology. 124:659-665

Thrombin activatable fibrinolysis inhibitor (TAFI) antigen levels exhibit a large interindividual variability in which genetic control seems to play a major role. However, recent reports have questioned the association between TAFI concentration and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e15383eb866759cf62980ee3ae0861c
https://doi.org/10.1111/j.1365-2141.2004.04824.x

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Preeclampsia and its interaction with common variants in thrombophilia genes

Autor: Frans M. Helmerhorst, E. T. M. Hille, S. Buitendijk, Mieke W. J. C. Jansen, Juriy W. Wladimiroff, C.J.M. de Groot, R M Bertina, M.P.M. de Maat, Kitty W.M. Bloemenkamp, Hans L. Vos

Publikováno v: Journal of Thrombosis and Haemostatis, 9, 2, 1588-1593
Journal of thrombosis and haemostasis, 2(9), 1588-1593. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 2, 1588-1593. Wiley-Blackwell Publishing Ltd

Recently, it has been proposed that abnormalities in coagulation and fibrinolysis contribute to the development of preeclampsia by increasing the thrombotic tendency. This hypothesis was tested in women who have had preeclampsia (cases) compared with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36dc5ac4ddc54f8ce035e64c4bc13f44
https://doi.org/10.1111/j.1538-7836.2004.00861.x

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Linkage analysis of factor VIII and von Willebrand factor loci as quantitative trait loci

Autor: L. A. Sandkuijl, M. de Visser, F. R. Rosendaal, R M Bertina, Ruud Lensen, H. L. Vos

Publikováno v: Journal of Thrombosis and Haemostasis. 1:1771-1776

Summary. Elevated factor (F)VIII levels contribute to venous thrombotic risk. FVIII levels are determined to a large extent by levels of von Willebrand factor (VWF), its carrier protein which protects FVIII against proteolysis. VWF levels are largely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b587f3327ee78de4d7637936db7fdb4e
https://doi.org/10.1046/j.1538-7836.2003.00314.x

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The activated protein C (APC)-resistant phenotype of APC cleavage site mutants of recombinant factor V in a reconstituted plasma model

Autor: Guido Tans, R M Bertina, Richard J. Dirven, Hans L. Vos, Jan Rosing, M. Van Der Neut Kolfschoten

Publikováno v: Blood Coagulation & Fibrinolysis. 13:207-215

Recently, new missense mutations in the activated protein C (APC) cleavage sites of human factor V (FV) distinct from the R506Q (FV Leiden) mutation have been reported. These mutations affect the APC cleavage site at arginine (Arg) 306 in the heavy c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d42066028146cc5c491c47a72d772248
https://doi.org/10.1097/00001721-200204000-00006

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