Zobrazeno 1 - 10
of 13
pro vyhledávání: '"R M, Van Frank"'
Autor:
P. J. Burck, L. J. Boxer, R. E. Zimmerman, L. E. Mattler, Nils U. Bang, M. L. Chang, C. A. Marks, R. M. Van Frank
Publikováno v:
Annals of the New York Academy of Sciences. 370:568-587
Publikováno v:
Biochemical and Biophysical Research Communications. 37:697-704
Subfractionation of rat liver microsomes by the use of rate-zonal centrifugation has been carried out using both normal and induced rats. Phenobarbital and methyl cholanthrene were found to have very distinctive effects on the distribution of cytochr
Publikováno v:
Experimental Biology and Medicine. 144:304-307
SummaryPseudomonas phaseolicola bacteriophage ⊘6 containing DS-RNA is capable of inducing interferon with a lower potency than with mycophage obtained from Penicillium stoloniferum. The smaller response with ⊘6 appears to be due to the lipid enve
Publikováno v:
The Journal of Immunology. 94:475-481
Summary Studies leading to the development and use of a one-dose potency test for poliomyelitis vaccine are described. The test is based on the measurement of neutralizing antibody in the serum of 6-week-old chickens that received one dose of a singl
Publikováno v:
Canadian Journal of Microbiology. 19:97-103
A mycovirus has been purified from mycelia of Penicillium chrysogenum by isopycnic centrifugation in sucrose and in CsCl. Viral particles band with a buoyant density of 1.20 in sucrose and 1.38 in CsCl. Particles have icosohedral symmetry, are 35 nm
Autor:
R. M. Van Frank, J. F. Lavender
Publikováno v:
Applied Microbiology. 22:358-365
Rabies virus produced in duck embryo cell culture was concentrated from volumes of 14 to 30 liters to 400 to 800 ml by zonal centrifugation. Virus titers of peak fractions were from 100- to 1,000-fold greater than those of the starting material. Vacc
Autor:
P. A. Reynolds, R. Stanzak, K. L. Cox, E. T. Seno, Charles Lee Hershberger, Jeffrey Lynn Larson, V. A. Birmingham, Wu-Kuang Yeh, Fishman Scott Eric, R. M. van Frank
Publikováno v:
Journal of natural products. 49(6)
A substantial amount of information on the biosynthesis of tylosin has been obtained over the past ten years. Physiological studies and experiments with tylosin-blocked (tyl) mutants have suggested the probable pathway by which tylactone is converted
Autor:
R E, Smith, R M, van Frank
Publikováno v:
Frontiers of biology. 43(4)
Publikováno v:
Science (New York, N.Y.). 215(4533)
Escherichia coli that has been genetically manipulated by recombinant DNA technology to synthesize human insulin polypeptides (A chain, B chain, or proinsulin) contains prominent cytoplasmic inclusion bodies. The amount of inclusion product within th
Publikováno v:
European journal of cell biology. 31(2)
Immunocytochemical techniques were used to identify human proinsulin chimeric protein in cytoplasmic inclusion bodies of genetically modified Escherichia coli. Antibodies to proinsulin chimeric protein (human proinsulin coupled at its amino-terminus