Zobrazeno 1 - 10
of 12
pro vyhledávání: '"R M, Solano"'
Autor:
Ingrid Langer, Jason Perret, Johnny Cnudde, Patrick Robberecht, Pascale Vertongen, R M Solano, Magali Waelbroeck
Publikováno v:
British Journal of Pharmacology. 136:1042-1048
1: We investigated the human vasoactive intestinal polypeptide (VIP) receptors VPAC(1) and VPAC(2) mutated at conserved tyrosine residues in the first transmembrane helix (VPAC(1) receptor Y146A and Y150A and VPAC(2) receptor Y130A and Y134A). 2: [(1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd110f3f23614f665b984eef988b36f1
https://doi.org/10.1038/sj.bjp.0704802
https://doi.org/10.1038/sj.bjp.0704802
Autor:
Pascale Vertongen, R M Solano, Jason Perret, Magali Waelbroeck, Patrick Robberecht, M. G. Juarranz
Publikováno v:
Peptides. 22:1363-1370
Inspection of the amino acid sequence of the human VPAC1 and the VPAC2 receptors after alignment of the conserved residues indicates that the second extracellular loop (EC2) is one amino acid shorter in the VPAC1 receptor due to the lack of a proline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed95202a456bbad79f70fee40197f83
https://doi.org/10.1016/s0196-9781(01)00476-4
https://doi.org/10.1016/s0196-9781(01)00476-4
Autor:
Ingrid Langer, Jason Perret, R M Solano, Magali Waelbroeck, Patrick Robberecht, Pascale Vertongen
Publikováno v:
British Journal of Pharmacology. 133:1249-1254
1. We investigated the role of two conserved basic residues in the second transmembrane helix arginine 172 (R172) and lysine 179 (K179) of the VPAC(2) receptor. 2. Vasoactive intestinal polypeptide (VIP) activated VPAC(2) receptors with an EC(50) val
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85b62c88ddfec061396000a6beb0b7e9
https://doi.org/10.1038/sj.bjp.0704195
https://doi.org/10.1038/sj.bjp.0704195
Autor:
Pascale Vertongen, M. G. Juarranz, R M Solano, Jason Perret, Ingrid Langer, Magali Waelbroeck, Patrick Robberecht
Publikováno v:
Journal of Biological Chemistry. 276:1084-1088
We mutated the vasoactive intestinal peptide (VIP) Asp(3) residue and two VPAC(1) receptor second transmembrane helix basic residues (Arg(188) and Lys(195)). VIP had a lower affinity for R188Q, R188L, K195Q, and K195I VPAC(1) receptors than for VPAC(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d378b17f31b32f434c73269f564d56de
https://doi.org/10.1074/jbc.m007696200
https://doi.org/10.1074/jbc.m007696200
Autor:
Christine Delporte, Jason Perret, Patrick Robberecht, Jean Van Rampelbergh, Magali Waelbroeck, Antoine Bondue, R M Solano, Maria-Guillerma Juarranz, Philippe De Neef
Publikováno v:
British Journal of Pharmacology. 130:819-826
Vasoactive Intestinal Polypeptide (VIP) interacts with a high affinity to two subclasses of G protein coupled receptors named VPAC(1) and VPAC(2), and has a 3 - 10 fold preference for VPAC(1) over VPAC(2) receptors. Selective ligands for each recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f92461759507d88ae92a1a71a77d0325
https://doi.org/10.1038/sj.bjp.0703384
https://doi.org/10.1038/sj.bjp.0703384
Publikováno v:
Actas urologicas espanolas. 29(10)
To deep in the knowledge of the involvement of G-protein alphas and alphai subunits in human prostate cancer.Prostate tissue from 9 patients undergoing radical prostatectomy for prostate cancer and 5 controls undergoing cystoprostatectomy for bladder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db9384ff7af7925bf2621dcb0b22874a
https://pubmed.ncbi.nlm.nih.gov/16447592
https://pubmed.ncbi.nlm.nih.gov/16447592
Autor:
M J, Casarejos, R M, Solano, J, Menéndez, J A, Rodríguez-Navarro, C, Correa, J, García de Yébenes, M A, Mena
Publikováno v:
Journal of neurochemistry. 94(4)
l-DOPA is the most effective treatment for Parkinson's disease but in isolated neuronal cultures it is neurotoxic for dopamine (DA) neurones. Experiments in vivo and clinical studies have failed to show toxicity of l-DOPA in animals or patients but t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e674d6c68efb510aa45bd90f4a9b3663
https://pubmed.ncbi.nlm.nih.gov/16000163
https://pubmed.ncbi.nlm.nih.gov/16000163
Publikováno v:
British journal of pharmacology. 136(7)
1: We investigated the human vasoactive intestinal polypeptide (VIP) receptors VPAC(1) and VPAC(2) mutated at conserved tyrosine residues in the first transmembrane helix (VPAC(1) receptor Y146A and Y150A and VPAC(2) receptor Y130A and Y134A). 2: [(1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b6b32debd863eb4ae992a4e9d5a0a2a
https://pubmed.ncbi.nlm.nih.gov/12145104
https://pubmed.ncbi.nlm.nih.gov/12145104
Autor:
M O, García-Fernández, R M, Solano, M, Sánchez-Chapado, A, Ruiz-Villaespesa, J C, Prieto, M J, Carmena
Publikováno v:
The Journal of urology. 166(6)
Because of increasing interest in G protein regulation of cell growth, differentiation and oncogenesis, we studied the functionality and expression of different G protein subunits in human prostate adenocarcinoma.Surgical prostate specimens from cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::703fba5b8fb618dd04b05a0b4ef0b7f5
https://pubmed.ncbi.nlm.nih.gov/11696820
https://pubmed.ncbi.nlm.nih.gov/11696820
Autor:
R M, Solano, M O, García-Fernández, C, Clemente, M, Querol, F, Bellamy, M, Sanchez-Chapado, J C, Prieto, M J, Carmena
Publikováno v:
The Prostate. 45(3)
Tadenan (a Pygeum africanum extract) is a drug used in the treatment of benign prostatic hyperplasia. Its effects on prostate fibroblast proliferation and bladder function after partial outlet obstruction have been demonstrated in various pharmacolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45039b6a9a66966ff5fc092761535681
https://pubmed.ncbi.nlm.nih.gov/11074527
https://pubmed.ncbi.nlm.nih.gov/11074527