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pro vyhledávání: '"R M, Saecker"'
Publikováno v:
Proteins.
A denaturant m-value is the magnitude of the slope of a typically linear plot of the unfolding free energy change DeltaG degrees (obs) vs. molar concentration (C(3)) of denaturant. For a given protein, the guanidinium chloride (GuHCl) m-value is appr
Autor:
O V, Tsodikov, R M, Saecker, S E, Melcher, M M, Levandoski, D E, Frank, M W, Capp, M T, Record
Publikováno v:
Journal of molecular biology. 294(3)
In our studies of lac repressor tetramer (T)-lac operator (O) interactions, we observed that the presence of extended regions of non-operator DNA flanking a single lac operator sequence embedded in plasmid DNA produced large and unusual cooperative a
Publikováno v:
Journal of molecular biology. 283(4)
Formation of many site-specific protein-nucleic acid complexes involves sequential conformational changes subsequent to initial binding which create functionally active assemblies. Characterization of population distributions and structural character
Publikováno v:
Journal of molecular biology. 283(4)
Kinetic studies of formation and dissociation of open-promoter complexes (RPo) involving Esigma70 RNA polymerase (R) and the lambdaPR promoter (P) demonstrate the existence of two kinetically significant intermediates, designated I1 and I2, and facil