Zobrazeno 1 - 10
of 13
pro vyhledávání: '"R M, Pascale"'
Publikováno v:
Critical reviews in oncogenesis. 11(1)
In this review, genetic changes known to occur in human and experimental animal hepatocarcinogenesis are evaluated comparatively, with the aim of identifying genes that could potentially be targets of new preventive and therapeutic strategies, albeit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::370bb36e7aecdb33640fc2155162acef
https://pubmed.ncbi.nlm.nih.gov/10795626
https://pubmed.ncbi.nlm.nih.gov/10795626
Autor:
M R, De Miglio, F, Canzian, R M, Pascale, M M, Simile, M R, Muroni, D, Calvisi, G, Romeo, F, Feo
Publikováno v:
Cancer research. 59(18)
Neoplastic liver nodules and hepatocellular carcinomas (HCCs) were induced, by "resistant hepatocyte" model, 32 and 70 weeks after initiation with diethylnitrosamine, respectively, in F344 Brown Norway (BN), and (BNxF344)F1 rats. Nodule number/liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6aac814a5c4dc3f1c388f3f262c85155
https://pubmed.ncbi.nlm.nih.gov/10493520
https://pubmed.ncbi.nlm.nih.gov/10493520
Autor:
R M, Pascale, M R, De Miglio, M R, Muroni, M M, Simile, L, Daino, M A, Seddaiu, A, Nufris, L, Gaspa, L, Deiana, F, Feo
Publikováno v:
International journal of cancer. 68(1)
We have investigated by restriction fragment analysis genomic abnormalities involving the c-myc gene in DNA isolated from adenomas and hepatocellular carcinomas (HCCs). Adenomas and HCCs were induced by the "resistant hepatocyte" protocol in diethyln
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a20ba9f72e6c7e7815e17f103af417df
https://pubmed.ncbi.nlm.nih.gov/8895554
https://pubmed.ncbi.nlm.nih.gov/8895554
Publikováno v:
Carcinogenesis. 17(8)
The phylogenetically distant F344 and BN rat strains and their (BN x F344) F1 hybrids were compared for susceptibility to hepatocarcinogenesis using the 'resistant hepatocyte' model. Quantitative stereological analysis of frequency (number/liver) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6661eb6281eadf17040cd417285db170
https://pubmed.ncbi.nlm.nih.gov/8761440
https://pubmed.ncbi.nlm.nih.gov/8761440
Autor:
U, Gerbracht, E, Eigenbrodt, M M, Simile, R M, Pascale, L, Gaspa, L, Daino, M A, Seddaiu, M R, De Miglio, A, Nufris, F, Feo
Publikováno v:
Anticancer research. 13(6A)
gamma-Glutamyltranspeptidase (GGT)-positive foci and glutathione-S-transferase, placental (GST-P)-positive lesions occupied 36% and 54% of liver parenchyma, respectively, in Wistar rats 8 weeks after initiation with diethylnitrosamine, followed by se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b7e819d4e4342bb3e056524873f9c33
https://pubmed.ncbi.nlm.nih.gov/8297102
https://pubmed.ncbi.nlm.nih.gov/8297102
Publikováno v:
Anticancer research. 13(5A)
Carcinogenesis is a complex process characterized by the cumulative activation of various oncogenes and the inactivation of suppressor genes. Epigenetic mechanisms are also involved. Mutational activation of ras family genes occurs in most spontaneou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b095b4f271b3424a9f25b62833a4015c
https://pubmed.ncbi.nlm.nih.gov/8239505
https://pubmed.ncbi.nlm.nih.gov/8239505
Publikováno v:
Research communications in chemical pathology and pharmacology. 81(2)
Highly purified 5-l-methyltetrahydrofolate (m-THF) and 5-l-formyl-THF (f-THF) preparations were compared for rescuing from methotrexate (MTX) toxicity in DBA2 mice transplanted with L1210 leukemia. Mice received two doses of reduced folates (2 mg/kg,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7b6ec64704f679e4c4109b34d0c6bcb
https://pubmed.ncbi.nlm.nih.gov/8210704
https://pubmed.ncbi.nlm.nih.gov/8210704
Chemoprevention of rat liver carcinogenesis by S-adenosyl-L-methionine: is DNA methylation involved?
Autor:
R M, Pascale, M M, Simile, M A, Seddaiu, L, Daino, M A, Vinci, G, Pinna, S, Bennati, L, Gaspa, F, Feo
Publikováno v:
Basic life sciences. 61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af4638f84b7bb3e184369d941b16cebe
https://pubmed.ncbi.nlm.nih.gov/8304933
https://pubmed.ncbi.nlm.nih.gov/8304933
Autor:
R M, Pascale, V, Marras, M M, Simile, L, Daino, G, Pinna, S, Bennati, M, Carta, M A, Seddaiu, G, Massarelli, F, Feo
Publikováno v:
Cancer research. 52(18)
Previous work has shown a consistent fall in S-adenosyl-L-methionine (SAM) in the liver of diethylnitrosamine-initiated rats, during the development of preneoplastic lesions, in persistent nodules (PNs), and hepatocellular carcinomas. The injection o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06a3825f51b16827555166b9162dfca1
https://pubmed.ncbi.nlm.nih.gov/1516054
https://pubmed.ncbi.nlm.nih.gov/1516054
Autor:
R M, Pascale, M M, Simile, G, Satta, M A, Seddaiu, L, Daino, G, Pinna, M A, Vinci, L, Gaspa, F, Feo
Publikováno v:
Anticancer research. 11(4)
Male Wistar rats, initiated with diethylnitrosamine (DENA), were subjected to a selection treatment, according to the "resistant hepatocyte" model, followed or not followed by phenobarbital (PB). Rats received, for 3 weeks after selection, 4 i.m. dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3700805cff033039298cb0e461adf4e9
https://pubmed.ncbi.nlm.nih.gov/1684097
https://pubmed.ncbi.nlm.nih.gov/1684097