Zobrazeno 1 - 10
of 36
pro vyhledávání: '"R M, Naclerio"'
Publikováno v:
Rhinology journal. 48:318-324
Evidence suggests IgE may play a role in chronic rhinosinusitis (CRS). We sought to determine if treatment with a monoclonal antibody against IgE (omalizumab) is effective in reducing CRS inflammation. We performed a randomized, double blind, placebo
Autor:
M. WAGENMANN, F. M. BAROODY, M. DESROSIERS, W. C. HUBBARD, S. FORD, L. M. LICHTENSTEIN, R. M. NACLERIO
Publikováno v:
Clinical Experimental Allergy. 26:371-378
Publikováno v:
The Journal of Immunology. 148:2223-2228
The pattern of mediators and appearance of cells that stain with alcian blue during human experimental early and late phase allergic reactions suggest that basophils accumulate in nasal secretions within hours of local Ag stimulation. To further expl
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 31(12)
Inhalation of hot, humid air (HHA: 37 degrees C,95% relative humidity (RH)) partially inhibits the early response to nasal challenge with antigen.To investigate whether HHA inhibited the late-phase response to nasal challenge with antigen and increas
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 28(1)
Neuronal involvement has been implicated in the pathophysiology of non-allergic and allergic rhinitis, contributing to the typical exacerbation of these conditions upon exposure to non-specific environmental irritants.To determine if non-allergic and
Autor:
R M, Naclerio, D, Proud, B, Moylan, S, Balcer, L, Freidhoff, A, Kagey-Sobotka, L M, Lichtenstein, P S, Creticos, R G, Hamilton, P S, Norman
Publikováno v:
The Journal of allergy and clinical immunology. 100(3)
Immunotherapy effectively treats the symptoms of allergic rhinitis and improves its pathophysiology. We studied whether the effects of immunotherapy on the early response to nasal challenge with antigen and seasonal symptoms persist after discontinua
Autor:
M, Wagenmann, F M, Baroody, M, Desrosiers, W C, Hubbard, S, Ford, L M, Lichtenstein, R M, Naclerio
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 26(4)
Multiple mediators including prostaglandin D2 and leukotriene B4 have been shown to increase in nasal secretions during the early response to nasal challenge with antigen.Our objective was to investigate the time course of prostanoid and leukotriene
Autor:
R M, Naclerio
Publikováno v:
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 109(3 Pt 2)
The high prevalence of allergic rhinitis requires all physicians and surgeons to have a fundamental understanding of this disease. Fortunately, patients with allergic rhinitis can be diagnosed accurately and prescribed effective treatment for symptom
Autor:
R M, Naclerio
Publikováno v:
Annals of allergy. 71(3)
The nasal antigen challenge model has proved useful in assessing the roles of inflammatory mediators in the clinical allergic response. Studies using this model have revealed that the acute allergic response is associated with increased concentration
Autor:
F M, Baroody, R M, Naclerio
Publikováno v:
Otolaryngologic clinics of North America. 26(4)
We have provided an overview of the immune system and its components. These components--cell-mediated and humoral immunity, the complement system and the different phagocytic cells--all function in concert to protect the body from foreign invaders. W