Výsledky vyhledávání - "R M, Mannhold"

Computer classification models on the relationship between chemical structures of compounds and drugs with their blood brain barrier penetration

Autor: O A, Raevskiĭ, S L, Solodova, O E, Raevskaia, Ia V, Liplavskiĭ, R M, Mannhold

Publikováno v: Biomeditsinskaya Khimiya. 58:246-256

Ability of drugs to cross blood-brain barrier (BBB) (BBB+ for BBB-penetrating and BBB- for non-penetrating compounds) is one of the most important properties of chemicals acting on the central nervous system (CNS). This work presents the results of m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c0e3758429ec90ca75caa949c9061b
https://doi.org/10.18097/pbmc20125803246

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Molecular pharmacological aspects of antiarrhythmic activity. I. Class I and class III compounds and lipid peroxidation

Autor: E, Rekka, R M, Mannhold, A, Bast, H, Timmerman

Publikováno v: Biochemical pharmacology. 39(1)

The effect of nineteen antiarrhythmic agents on nonenzymatic lipid peroxidation, using rat hepatic microsomes, was studied. Lipid peroxidation was induced by Fe2(+)-ascorbic acid and assayed spectrophotometrically by measuring the 2-thiobarbituric ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2f21b527d662affeb2d8fc3a4f48f552
https://pubmed.ncbi.nlm.nih.gov/2297363

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