Zobrazeno 1 - 7
of 7
pro vyhledávání: '"R M, Lyall"'
Autor:
T, Yoneda, R M, Lyall, M M, Alsina, P E, Persons, A P, Spada, A, Levitzki, A, Zilberstein, G R, Mundy
Publikováno v:
Cancer research. 51(16)
Many human tumors of epithelial origin contain cells overexpressing the epidermal growth factor (EGF) receptor, and there is convincing evidence that cancer cell growth is correlated with the loss of the normal regulation of the EGF receptor signal t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4dd195afc3cad62f07543007d7dab2f
https://pubmed.ncbi.nlm.nih.gov/1651159
https://pubmed.ncbi.nlm.nih.gov/1651159
Autor:
R M Lyall, Gene P. Siegal, Unnur P. Thorgeirsson, R DiFlorio, Lance A. Liotta, Terranova Vp, E S Hujanen, Elliott Schiffmann
Publikováno v:
Journal of Clinical Investigation. 77:1180-1186
Polymorphonuclear neutrophils (PMN) traverse basement membrane to reach sites of infection. We have studied the role of laminin, a specific basement membrane component, in this process using three assay systems. In the Boyden chamber, laminin was fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc67a6d1eab389f9928e5481055f5152
https://doi.org/10.1172/jci112419
https://doi.org/10.1172/jci112419
Publikováno v:
The Journal of Cell Biology
The response of human endothelial cell migration to various extracellular matrix components and growth factors has been assessed. Human endothelial cells demonstrate increased chemotaxis and chemokinesis when placed in a modified Boyden chamber with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84db58dd09e60f2faf640d040824d0f
https://doi.org/10.1083/jcb.101.6.2330
https://doi.org/10.1083/jcb.101.6.2330
Autor:
Thomas J. Dull, Axel Ullrich, Joseph Schlessinger, E Van Obberghen, D. Szapary, Annemarie Honegger, R M Lyall, A Schmidt
Publikováno v:
Molecular and Cellular Biology. 7:4568-4571
Cultured NIH-3T3 cells devoid of endogenous epidermal growth factor (EGF) receptors were transfected with cDNA expression constructs encoding either normal human EGF receptor or a receptor mutated in vitro at Lys-721, a residue that is thought to fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a070deb1c00fb90f86dae5e72074b07
https://doi.org/10.1128/mcb.7.12.4568
https://doi.org/10.1128/mcb.7.12.4568
Publikováno v:
The Biochemical journal. 185(1)
The DNA-binding site of a previously characterized non-histone chromosomal protein antigen(s) from HeLa cells was investigated for its species specificity. Treatment with large amounts of micrococcal nuclease abolishes immunoactivity, which can then
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583f6869410706aad3bec8aa0e33f001
https://pubmed.ncbi.nlm.nih.gov/6769431
https://pubmed.ncbi.nlm.nih.gov/6769431
Publikováno v:
The EMBO journal. 7(4)
Acidic fibroblast growth factor (aFGF), a polypeptide with a mol. wt of approximately 16,000, is a potent mitogen for a variety of cells and shares 55% amino acid sequence identity with basic FGF. The recent isolation of three new oncogenes which sha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772a4b71c6c8cb3b0454025244240e61
https://pubmed.ncbi.nlm.nih.gov/2841120
https://pubmed.ncbi.nlm.nih.gov/2841120
Publikováno v:
Cancer research. 47(11)
Mutants of the human KB carcinoma cell line resistant to a cytotoxic conjugate of epidermal growth factor (EGF) and Pseudomonas exotoxin (PE) were selected. EGF-PE and the drug verapamil, which enhanced EGF-PE cytotoxicity, were used in the selection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af4ddc8f8b14a62f80cf3261836c7c70
https://pubmed.ncbi.nlm.nih.gov/3494506
https://pubmed.ncbi.nlm.nih.gov/3494506