Zobrazeno 1 - 9
of 9
pro vyhledávání: '"R M, Linden"'
Publikováno v:
Gene therapy
Viral vectors derived from adeno-associated viruses (AAV) are widely used for gene transfer both in vitro and in vivo. The increasing use of AAV as a gene transfer vector, as well as recently demonstrated immunological complications in clinical trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30dddc8bee9a4e188f89af0b83cbbd9c
http://europepmc.org/articles/PMC2900506
http://europepmc.org/articles/PMC2900506
Publikováno v:
Current Genetics. 19:375-381
Rapidly growing cultures of N. crassa do not produce laccase. Exposure of this fungus to different inducing agents leads to a de novo biosynthesis of extracellular laccase in vegetative cultures. In this study the induction of laccase after addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d82c877be37fdc0b1613e3b16355d3
https://doi.org/10.1007/bf00309598
https://doi.org/10.1007/bf00309598
Autor:
R M, Linden, K I, Berns
Publikováno v:
Contributions to microbiology. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54febc343340b8cba03f2248b4f107d2
https://pubmed.ncbi.nlm.nih.gov/10941571
https://pubmed.ncbi.nlm.nih.gov/10941571
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 93(21)
Adeno-associated virus (AAV) has attracted considerable interest as a potential vector for gene delivery. Wild-type virus is notable for the lack of association with any human disease and the ability to stably integrate its genome in a site-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac764fc13f107f536a44cd7fdee52db
https://pubmed.ncbi.nlm.nih.gov/8876128
https://pubmed.ncbi.nlm.nih.gov/8876128
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 93(15)
The adeno-associated virus (AAV) genome integrates site specifically into a defined region of human chromosome 19 (termed AAVS1). Using a functional assay for AAV integration into AAVS1 DNA propagated as an episome, we obtained evidence that a 33-nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eabf67cfc76c9603e28d93426f890d88
https://pubmed.ncbi.nlm.nih.gov/8755586
https://pubmed.ncbi.nlm.nih.gov/8755586
Autor:
R M Linden, Kenneth I. Berns
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 17(3)
Although 80-90% of adults are seropositive for antibodies against the human parvovirus adeno-associated virus (AAV), infection has not been associated with either symptoms or disease. In cell culture, AAV infection is not productive unless there is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c67c149b44d8ad3048a78a37ee25865
https://pubmed.ncbi.nlm.nih.gov/7748178
https://pubmed.ncbi.nlm.nih.gov/7748178
Publikováno v:
Current genetics. 22(3)
Laccase from the ascomycete Neurospora crassa is an inducible secretory enzyme. In vegetatively growing cultures its biosynthesis is repressed but can be induced by different protein synthesis inhibitors. Transformation of the N. crassa wild-type str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740373a61318098ac1be63a56c4caa22
https://pubmed.ncbi.nlm.nih.gov/1388108
https://pubmed.ncbi.nlm.nih.gov/1388108
Autor:
R. M. Linden, Savio L. C. Woo
Publikováno v:
Nature Medicine. 5:21-22
Using a recombinant adeno-associated virus vector to deliver the factor IX gene, two groups achieve long-term partial correction of hemophilia B in a canine model of the disease (pages 56–70).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::098786075341cd0ccac1b2dfa66fc230
https://doi.org/10.1038/4698
https://doi.org/10.1038/4698