Zobrazeno 1 - 10
of 257
pro vyhledávání: '"R M, Linden"'
Publikováno v:
Gene therapy
Viral vectors derived from adeno-associated viruses (AAV) are widely used for gene transfer both in vitro and in vivo. The increasing use of AAV as a gene transfer vector, as well as recently demonstrated immunological complications in clinical trial
Publikováno v:
Bulgarian Journal of Veterinary Medicine. Sep2024, Vol. 27 Issue 3, p357-363. 7p.
Autor:
Dai, Shang1,2 (AUTHOR), Wang, Binqiang1,3,4 (AUTHOR), Ye, Rui5 (AUTHOR), Zhang, Dong1,5 (AUTHOR), Xie, Zhenming1 (AUTHOR), Yu, Ning1 (AUTHOR), Cai, Chunhui1 (AUTHOR), Huang, Cheng1 (AUTHOR), Zhao, Jie1 (AUTHOR), Zhang, Furong1 (AUTHOR), Hua, Yuejin1,6 (AUTHOR) yjhua@zju.edu.cn, Zhao, Ye1,6 (AUTHOR) yezhao@zju.edu.cn, Zhou, Ruhong1,2,5,6 (AUTHOR) rhzhou@zju.edu.cn, Tian, Bing1,6 (AUTHOR) tianbing@zju.edu.cn
Publikováno v:
Advanced Science. 7/10/2024, Vol. 11 Issue 26, p1-12. 12p.
Publikováno v:
Current Genetics. 19:375-381
Rapidly growing cultures of N. crassa do not produce laccase. Exposure of this fungus to different inducing agents leads to a de novo biosynthesis of extracellular laccase in vegetative cultures. In this study the induction of laccase after addition
Autor:
R M, Linden, K I, Berns
Publikováno v:
Contributions to microbiology. 4
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 93(21)
Adeno-associated virus (AAV) has attracted considerable interest as a potential vector for gene delivery. Wild-type virus is notable for the lack of association with any human disease and the ability to stably integrate its genome in a site-specific
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 93(15)
The adeno-associated virus (AAV) genome integrates site specifically into a defined region of human chromosome 19 (termed AAVS1). Using a functional assay for AAV integration into AAVS1 DNA propagated as an episome, we obtained evidence that a 33-nuc
Autor:
R M Linden, Kenneth I. Berns
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 17(3)
Although 80-90% of adults are seropositive for antibodies against the human parvovirus adeno-associated virus (AAV), infection has not been associated with either symptoms or disease. In cell culture, AAV infection is not productive unless there is a
Publikováno v:
Current genetics. 22(3)
Laccase from the ascomycete Neurospora crassa is an inducible secretory enzyme. In vegetatively growing cultures its biosynthesis is repressed but can be induced by different protein synthesis inhibitors. Transformation of the N. crassa wild-type str