Zobrazeno 1 - 10
of 12
pro vyhledávání: '"R M, Huff"'
D4 dopamine receptor-mediated signaling events determined in transfected Chinese hamster ovary cells
Publikováno v:
Journal of Biological Chemistry. 269:11813-11819
A Chinese hamster ovary (CHO) cell line stably expressing a recombinant human D4 dopamine receptor made from a synthetic gene has been used to determine potential D4-mediated signaling events. We designed and synthesized a modified gene coding for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebcea41444283b38b1419c0eaa75c35e
https://doi.org/10.1016/s0021-9258(17)32645-5
https://doi.org/10.1016/s0021-9258(17)32645-5
Autor:
L A, van Vliet, N, Rodenhuis, D, Dijkstra, H, Wikström, T A, Pugsley, K A, Serpa, L T, Meltzer, T G, Heffner, L D, Wise, M E, Lajiness, R M, Huff, K, Svensson, S, Sundell, M, Lundmark
Publikováno v:
Journal of medicinal chemistry. 43(15)
Benzopyranoxazine (+)-7 (PD 128907) is the most dopamine (DA) D3 receptor-selective agonist presently known. The only structural feature which distinguishes 7 from the analogous nonselective naphthoxazines is an oxygen atom in the 6-position. To exte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::782735ee7101d97d5722e9d202f6bd4b
https://pubmed.ncbi.nlm.nih.gov/10956195
https://pubmed.ncbi.nlm.nih.gov/10956195
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa3f1ace2908c44368a443f6a8f37dc5
https://pubmed.ncbi.nlm.nih.gov/9327937
https://pubmed.ncbi.nlm.nih.gov/9327937
Autor:
K M, Merchant, G S, Gill, D W, Harris, R M, Huff, M J, Eaton, K, Lookingland, B S, Lutzke, R B, Mccall, M F, Piercey, P J, Schreur, V H, Sethy, M W, Smith, K A, Svensson, A H, Tang, P F, Vonvoigtlander, R E, Tenbrink
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 279(3)
Dopamine D2-like receptors play an important role in the pharmacotherapy of psychotic disorders. Molecular and cellular techniques have identified distinct gene products (D2-long, D2-short, D3 and D4) displaying the D2 receptor pharmacology. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::259d6fa65fe3dc2859628be188e3cc22
https://pubmed.ncbi.nlm.nih.gov/8968364
https://pubmed.ncbi.nlm.nih.gov/8968364
D4 dopamine receptor-mediated signaling events determined in transfected Chinese hamster ovary cells
Publikováno v:
The Journal of biological chemistry. 269(16)
A Chinese hamster ovary (CHO) cell line stably expressing a recombinant human D4 dopamine receptor made from a synthetic gene has been used to determine potential D4-mediated signaling events. We designed and synthesized a modified gene coding for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bfb85ebc626fcc5ab2cea5dc7af3f2f2
https://pubmed.ncbi.nlm.nih.gov/7512953
https://pubmed.ncbi.nlm.nih.gov/7512953
Publikováno v:
Molecular pharmacology. 45(1)
Recombinant rat D3 dopamine receptors heterologously expressed in Chinese hamster ovary (CHO) cells are functionally coupled to endogenous G proteins. The affinity of the receptors for agonists is regulated by guanine nucleotides in the same manner a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7dc105191bf0860d6e02708639ea9c46
https://pubmed.ncbi.nlm.nih.gov/8302280
https://pubmed.ncbi.nlm.nih.gov/8302280
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 267(3)
Several neurotransmitters that act through G protein-linked receptors have been shown to affect the growth rate of dividing cells. An analysis of the early signaling events that mediate this response revealed some novel activities for G protein-linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::639e5d4d8f838ff30cb4bcc8dbaff4f0
https://pubmed.ncbi.nlm.nih.gov/7903393
https://pubmed.ncbi.nlm.nih.gov/7903393
Publikováno v:
Nature. 343(6255)
OVEREXPRESSION of the D2dopamine receptor has been proposed to be part of the pathology of schizophrenia1.The isolation of a D2dopamine receptor clone has assisted the molecular characterization of D2 receptors2. We have now isolated an identical rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89acd19d611eff80a6e67cb70cf9da43
https://pubmed.ncbi.nlm.nih.gov/2137198
https://pubmed.ncbi.nlm.nih.gov/2137198
Publikováno v:
Journal of Biological Chemistry. 261:1105-1110
Bovine cerebral cortex contains two major substrates for ADP-ribosylation by pertussis toxin: a 39-kDa protein, alpha 39, and a 41-kDa protein, alpha 41 (Neer, E. J., Lok, J. M., and Wolf, L. G. (1984) J. Biol. Chem. 259, 14222-14229). Both of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d992a8b2f404fcb4a255ad8523c39408
https://doi.org/10.1016/s0021-9258(17)36060-x
https://doi.org/10.1016/s0021-9258(17)36060-x
Publikováno v:
Advances in prostaglandin, thromboxane, and leukotriene research. 19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f160eca522bfbc0668031325fc5340d
https://pubmed.ncbi.nlm.nih.gov/2526542
https://pubmed.ncbi.nlm.nih.gov/2526542