Zobrazeno 1 - 7
of 7
pro vyhledávání: '"R M, Hoet"'
Autor:
R C Roovers, A.P. de Bruine, R M Hoet, Hennie R. Hoogenboom, Simon E. Hufton, Jan-Willem Arends
Publikováno v:
Immunotechnology. 4:1-20
In recent years, the use of display vectors and in vitro selection technologies has transformed the way in which we generate ligands, such as antibodies and peptides, for a given target. Using this technology, we are now able to design repertoires of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35030498af229421c15281655d8086c7
https://doi.org/10.1016/s1380-2933(98)00007-4
https://doi.org/10.1016/s1380-2933(98)00007-4
Publikováno v:
Arthritis and rheumatism. 43(9)
To examine anti-double-stranded DNA (anti-dsDNA) IgG autoantibodies from the bone marrow of individuals with systemic lupus erythematosus (SLE).A library of single-chain variable fragments (scFv) was constructed from SLE bone marrow complementary DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1aebdc3ec4ce706be6600d2558def5bb
https://pubmed.ncbi.nlm.nih.gov/11014365
https://pubmed.ncbi.nlm.nih.gov/11014365
Publikováno v:
Journal of molecular biology. 294(3)
We have sequenced the heavy and light chain genes from 365 IgG(+) B cells and found that 24 (6.5 %) contain somatically introduced insertions or deletions. These insertions and deletions are clustered at "hot-spots" in the antigen-binding site and fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4fa9bc5c754ea7c223785eb1c5cc95d2
https://pubmed.ncbi.nlm.nih.gov/10610790
https://pubmed.ncbi.nlm.nih.gov/10610790
Publikováno v:
European journal of immunology. 30(1)
Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by the presence of high immunoglobulin serum titers, but the mechanism by which these arise remains unclear. It has been suggested that the disease is associated with s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be9c91eb11caf76497170281ea693284
https://pubmed.ncbi.nlm.nih.gov/10602048
https://pubmed.ncbi.nlm.nih.gov/10602048
Autor:
R M, Hoet, M, Pieffers, M H, Stassen, J, Raats, R, de Wildt, G J, Pruijn, F, van den Hoogen, W J, van Venrooij
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(6)
Abs to U1 RNA are frequently found in patients suffering from systemic lupus erythematosus overlap syndromes and Ab titers correlate with disease activity. We describe the isolation of the first human anti-U1 RNA autoantibodies from a combinatorial I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fef8ac20b9a80859d44e6c674f1cc95e
https://pubmed.ncbi.nlm.nih.gov/10477600
https://pubmed.ncbi.nlm.nih.gov/10477600
Publikováno v:
The Journal of biological chemistry. 273(21)
Detailed analysis of various heparan sulfate (HS) species is seriously hampered by a lack of appropriate tools, such as antibodies. We adopted phage display technology to generate anti-HS antibodies. A "single pot" semisynthetic human antibody phage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad3a1da29d24695908a962921108d54e
https://pubmed.ncbi.nlm.nih.gov/9582329
https://pubmed.ncbi.nlm.nih.gov/9582329
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