Zobrazeno 1 - 10
of 36
pro vyhledávání: '"R M, Hirschfeld"'
Autor:
R M, Hirschfeld
Publikováno v:
The Journal of clinical psychiatry. 62
The lifetime prevalence of bipolar I disorder is approximately 1%. However, the prevalence of bipolar spectrum disorder is substantially higher. Bipolar spectrum disorder is a longitudinal diagnosis characterized by abnormal mood swings comprising so
Autor:
J M, Russell, L M, Koran, J, Rush, R M, Hirschfeld, W, Harrison, E S, Friedman, S, Davis, M, Keller
Publikováno v:
Depression and anxiety. 13(1)
Anxiety commonly complicates the clinical presentation of depression and has been associated with poorer long-term outcome, but little information is available on the clinical correlates, and comparative effect on treatment response, of subsyndromic
Autor:
A C, Leon, P, Blier, L, Culpepper, J M, Gorman, R M, Hirschfeld, A A, Nierenberg, S P, Roose, J F, Rosenbaum, S M, Stahl, M H, Trivedi
Publikováno v:
The Journal of clinical psychiatry. 62
Although various published clinical studies have suggested that some antidepressants may have a more rapid onset of therapeutic effect than others, none of these trials was adequately designed to measure differential time to onset of effect. Thus, ex
Autor:
R M, Hirschfeld
Publikováno v:
Depression and anxiety. 11(4)
Sertraline was first developed and approved for the treatment of depression. However, considerable research has been conducted on its use in anxiety disorders. This paper reviews the data emerging from controlled and open trials of the use of sertral
Autor:
C L, Bowden, J R, Calabrese, S L, McElroy, L, Gyulai, A, Wassef, F, Petty, H G, Pope, J C, Chou, P E, Keck, L J, Rhodes, A C, Swann, R M, Hirschfeld, P J, Wozniak
Publikováno v:
Archives of general psychiatry. 57(5)
Long-term outcomes are often poor in patients with bipolar disorder despite treatment; more effective treatments are needed to reduce recurrences and morbidity. This study compared the efficacy of divalproex, lithium, and placebo as prophylactic ther
Autor:
R M, Hirschfeld
Publikováno v:
The Journal of clinical psychiatry. 61
The symptoms of depression can be improved by agents that act by various mechanisms to increase synaptic concentrations of monoamines. This finding led to the adoption of the monoamine hypothesis of depression, first put forward over 30 years ago, wh
Autor:
R M, Hirschfeld
Publikováno v:
Depression and anxiety. 10(4)
Depression and comorbid personality disorders relate to one another in three distinct ways: 1) personality disorders may precede the development of depression and render an individual vulnerable to depression; 2) depression may precede the personalit
Autor:
R M, Hirschfeld
Publikováno v:
The Journal of clinical psychiatry. 60
There are several possible causes of sexual dysfunction in depressed patients. A core symptom of depression is anhedonia, including loss of libido. Therefore, determining a cause of sexual dysfunction in a depressed patient can be very difficult, and
Publikováno v:
Depression and anxiety. 9(4)
One-third of patients with untreated depression have sexual difficulties manifested by decreased libido, erectile dysfunction or delayed ejaculation. This dysfunction may be exacerbated by stimulation of post-synaptic serotonin 5HT2 receptors, a side
Autor:
R M, Hirschfeld
Publikováno v:
The Journal of clinical psychiatry. 60
Sexual dysfunction occurs in over one third of the general population and has many causes, including psychosocial factors, general medical illness, nonpsychiatric medication, psychiatric disorders, and psychotropic medications. Psychosocial causes ar