Zobrazeno 1 - 10
of 19
pro vyhledávání: '"R M, Darrow"'
Publikováno v:
Photochemistry and Photobiology. 81:541-547
Autor:
S Shivaram, Gerald J. Chader, G Kutty, R K Kutty, D T Organisciak, B Wiggert, Paul Wong, R M Darrow, R T Fletcher
Publikováno v:
Biochemistry and Cell Biology. 72:499-503
Prolonged periods of high-intensity visible light exposure lead to photoreceptor cell degeneration, but the mechanism of damage is not understood. Increased clusterin mRNA levels have been found in several models of apoptosis, as well as in neurodege
Publikováno v:
Investigative ophthalmologyvisual science. 41(12)
To determine the relative susceptibility of rats to retinal light damage at different times of the day or night.Rats maintained in a dim cyclic light or dark environment were exposed to a single dose of intense green light beginning at various times.
Publikováno v:
Photochemistry and photobiology. 71(5)
The damaging effects of visible light on the mammalian retina can be detected as functional, morphological or biochemical changes in the photoreceptor cells. Although previous studies have implicated short-lived reactive oxygen species in these proce
Publikováno v:
Photochemistry and photobiology. 70(2)
In the rat, photoreceptor cell death from exposure to intense visible light can be prevented by prior treatment with antioxidants. In this study we subjected albino rats raised in dim cyclic light and rats made more susceptible to light damage by rea
Publikováno v:
Current eye research. 19(2)
To determine the effects of genetic background and light rearing conditions on intense-light-mediated retinal degeneration in young RCS rats.Albino rats, homozygous or heterozygous for the rdy gene were bred and born in dim cyclic light. At P7 they w
Publikováno v:
Photochemistry and photobiology. 69(1)
Intense visible light can damage retinal photoreceptor cells by photochemical or thermal processes, leading to cell death. The precise mechanism of light-induced damage is unknown; however, oxidative stress is thought to be involved, based on the pro
Publikováno v:
Investigative ophthalmologyvisual science. 39(7)
To determine the effects of age and long-term light- or dark-rearing environments on acute, intense-light-mediated retinal degeneration.Male albino rats were maintained in a dim cyclic light environment or in darkness for as long as 1 year. When aged
Publikováno v:
Investigative ophthalmologyvisual science. 37(11)
To compare retinal light damage in rats with either normal or reduced levels of rod outer segment (ROS) docosahexaenoic acid.Weanling male albino rats were maintained in a weak cyclic light environment and fed either a nonpurified control diet or a p
Publikováno v:
Investigative ophthalmologyvisual science. 36(6)
To study the time course of visual cell damage resulting from hyperthermic light exposure and the possible involvement of rod outer segment (ROS) lipids in the process.Rats were acclimated in darkness for 2 hours in a hyperthermic chamber to elevate