Zobrazeno 1 - 10
of 123
pro vyhledávání: '"R M, Conry"'
Publikováno v:
The journal of gene medicine. 2(2)
We have previously reported that intramuscular, intradermal or epidermal gene gun administration of a plasmid encoding carcinoembryonic antigen (CEA) under transcriptional regulatory control of the cytomegalovirus (CMV) early promoter/enhancer elicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd1b2e620307f2187b67d2fda63f95cf
https://pubmed.ncbi.nlm.nih.gov/10809147
https://pubmed.ncbi.nlm.nih.gov/10809147
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(1)
Carcinoembryonic antigen (CEA) is a well-characterized oncofetal glycoprotein whose overexpression by human adenocarcinomas has been a target for cancer immunotherapy. Limited information is available regarding the ability of patients to mount an ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0f3bdfd3d3b15cdc2ed5725702b4ffb
https://pubmed.ncbi.nlm.nih.gov/10656429
https://pubmed.ncbi.nlm.nih.gov/10656429
Autor:
R M, Conry, M B, Khazaeli, M N, Saleh, K O, Allen, D L, Barlow, S E, Moore, D, Craig, R B, Arani, J, Schlom, A F, LoBuglio
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(9)
The principal objectives of this trial were twofold: (a) to examine the safety and relative efficacy of intradermal needle injection versus s.c. jet administration of a carcinoembryonic antigen (CEA)-encoding recombinant vaccinia virus (rV-CEA) over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2064db30433b9de92e35236a3dbd716
https://pubmed.ncbi.nlm.nih.gov/10499601
https://pubmed.ncbi.nlm.nih.gov/10499601
Autor:
R M, Conry, S A, White, P N, Fultz, M B, Khazaeli, T V, Strong, K O, Allen, D L, Barlow, S E, Moore, P N, Coan, I, Davis, D T, Curiel, A F, LoBuglio
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(11)
In preparation for a Phase I trial of DNA immunization against carcinoembryonic antigen (CEA) in patients with colorectal carcinoma, we have produced a single plasmid DNA encoding CEA and hepatitis B surface antigen (HBsAg) under transcriptional regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41ca215f681c2e0b4736b9860babced3
https://pubmed.ncbi.nlm.nih.gov/9829759
https://pubmed.ncbi.nlm.nih.gov/9829759
Publikováno v:
Seminars in oncology. 23(1)
The novel observations that intramuscular injection of plasmid DNA preparations could result in myocyte gene expression and induce immune responses to encoded immunogens has generated intense interest in the form of gene therapy. This phenomena can o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d6e912f1ce1aac247acdc7290734cf04
https://pubmed.ncbi.nlm.nih.gov/8607023
https://pubmed.ncbi.nlm.nih.gov/8607023
Autor:
R M, Conry, G, Widera, A F, LoBuglio, J T, Fuller, S E, Moore, D L, Barlow, J, Turner, N S, Yang, D T, Curiel
Publikováno v:
Gene therapy. 3(1)
We sought to amplify the immune response to polynucleotide immunization through co-delivery of complementary DNA (cDNA) encoding a cytokine or co-stimulatory molecule to enhance antigen presentation. In the context of intramuscular immunization, we e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22a2067dcb6cc93ba0ce7be1708d5291
https://pubmed.ncbi.nlm.nih.gov/8929913
https://pubmed.ncbi.nlm.nih.gov/8929913
Publikováno v:
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy. 18(4)
In a phase I trial, eight patients with non-Hodgkin's B-cell lymphoma received mouse IgG1k monoclonal antibody HD37 specific for CD19 conjugated to deglycosylated ricin A chain (dgA) administered in four doses at 4-h intervals with total doses rangin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::164cb67ca3370198e549d8afc32a4af7
https://pubmed.ncbi.nlm.nih.gov/8680651
https://pubmed.ncbi.nlm.nih.gov/8680651
Autor:
R M, Conry, A F, LoBuglio, M, Wright, L, Sumerel, M J, Pike, F, Johanning, R, Benjamin, D, Lu, D T, Curiel
Publikováno v:
Cancer research. 55(7)
We have constructed mRNA transcripts encoding luciferase and human carcinoembryonic antigen (CEA) which are capped, polyadenylated, and stabilized by human beta-globin 5' and 3' untranslated regions. The mRNA construct encoding human CEA directed CEA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::770035344ceddcc8c3f2b81fd65253e9
https://pubmed.ncbi.nlm.nih.gov/7882341
https://pubmed.ncbi.nlm.nih.gov/7882341
Autor:
R M, Conry, A F, LoBuglio, F, Loechel, S E, Moore, L A, Sumerel, D L, Barlow, J, Pike, D T, Curiel
Publikováno v:
Cancer gene therapy. 2(1)
We have constructed a plasmid DNA encoding the full-length complementary DNA for human carcinoembryonic antigen (CEA) under transcriptional regulatory control of the cytomegalovirus early promoter/enhancer (pCEA) and demonstrated that this plasmid ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7298016e48fbe6da6417a01af5bdbfff
https://pubmed.ncbi.nlm.nih.gov/7621253
https://pubmed.ncbi.nlm.nih.gov/7621253
Publikováno v:
Gene therapy. 2(1)
We have constructed a plasmid DNA encoding the full-length cDNA for human carcinoembryonic antigen (CEA) driven by the cytomegalovirus early promoter/enhancer and demonstrated that this plasmid can function as a polynucleotide vaccine. The immune res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9668a9f6bc7e49f2245822cc09d5c228
https://pubmed.ncbi.nlm.nih.gov/7712333
https://pubmed.ncbi.nlm.nih.gov/7712333