Zobrazeno 1 - 10
of 777
pro vyhledávání: '"R Leroy"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Maternal metabolic disorders may cause lipotoxic effects on the developing oocyte. Understanding the timing at which this might disrupt embryo epigenetic programming and how this is linked with mitochondrial dysfunction is crucial for improv
Externí odkaz:
https://doaj.org/article/a3e67ac6e33d4a389c4d1b2936f7a23b
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Consumption of obesogenic (OB) diets increases the prevalence of maternal obesity worldwide, causing major psychological and social burdens in women. Obesity not only impacts the mother’s health and fertility but also elevates the risk of obesity a
Externí odkaz:
https://doaj.org/article/3abcc208a63e498b86dac969871fcfe2
Autor:
Inne Xhonneux, Waleed F A Marei, Ben Meulders, Jens Slootmans, Isabel Pintelon, Jo L M R Leroy
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0305912 (2024)
Diet-induced obesity reduces oocyte quality mainly by impacting oocyte mitochondrial functions. Moreover, maternal obesity is associated with mitochondrial dysfunction in oocytes of their adult offspring. However, these effects were reported only in
Externí odkaz:
https://doaj.org/article/f6ebe84f14a44b77be90dce52075c288
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Obesity affects oocyte mitochondrial functions and reduces oocyte quality and fertility. Obesity may also increase the risk of metabolic disorders in the offspring. Children are likely to follow their parents lifestyle and diet, which also contribute
Externí odkaz:
https://doaj.org/article/f378773d122649639278c2488d9215cc
Publikováno v:
Reproductive Biology and Endocrinology, Vol 19, Iss 1, Pp 1-21 (2021)
Abstract Background Maternal metabolic disorders are linked to reduced metabolic health and oocyte quality. Obese women are advised to lose weight before conception to increase pregnancy chances. However, as human studies show no univocal guidelines,
Externí odkaz:
https://doaj.org/article/66e1a3f8a8204d9aaa1d41b6f6216c8a
Publikováno v:
Biology, Vol 12, Iss 7, p 1016 (2023)
We investigated whether a high-fat/high-sugar (HF/HS) diet alters the lipidomic profile of the oviductal epithelium (OE) and studied the patterns of these changes over time. Female outbred Swiss mice were fed either a control (10% fat) or HF/HS (60%
Externí odkaz:
https://doaj.org/article/1e67c3a321b64fdea0cb1b0440b9057f
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0275379 (2022)
Research questionHow long does it take for an obesogenic (high-fat/high-sugar, HF/HS) diet to influence the oviductal microenvironment? What are the affected cellular pathways and are they dependent on the genetic background of the mouse model?Design
Externí odkaz:
https://doaj.org/article/b42402cc77a143bea96f1558429d864a
