Zobrazeno 1 - 10
of 66
pro vyhledávání: '"R Lee Reinhardt"'
Autor:
Ivy K Brown, Nathan Dyjack, Mindy M Miller, Harsha Krovi, Cydney Rios, Rachel Woolaver, Laura Harmacek, Ting-Hui Tu, Brian P O'Connor, Thomas Danhorn, Brian Vestal, Laurent Gapin, Clemencia Pinilla, Max A Seibold, James Scott-Browne, Radleigh G Santos, R Lee Reinhardt
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009602 (2021)
The CD4+ T cell response is critical to host protection against helminth infection. How this response varies across different hosts and tissues remains an important gap in our understanding. Using IL-4-reporter mice to identify responding CD4+ T cell
Externí odkaz:
https://doaj.org/article/bfee9113d1934b3d8063baf5f57b2905
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39750 (2012)
Interleukin (IL)-17A plays an important role in host defense against a variety of pathogens and may also contribute to the pathogenesis of autoimmune diseases. However, precise identification and quantification of the cells that produce this cytokine
Externí odkaz:
https://doaj.org/article/25df3642da8748f6a293eb9bb2174fe8
Autor:
Haolin Liu, Katja Aviszus, Pearlanne Zelarney, Shu-Yi Liao, Anthony N. Gerber, Barry Make, Michael E. Wechsler, Philippa Marrack, R. Lee Reinhardt
Publikováno v:
ERJ Open Research, Vol 9, Iss 5 (2023)
Background While vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) provides significant protection from coronavirus disease 2019, the protection afforded to individuals with chronic lung disease is less well established
Externí odkaz:
https://doaj.org/article/fa82baa5e3094421903024746f9258a4
Autor:
Byron W. Hayes, Francis M. Hughes, Cassandra Phoenix, Yuxuan Miao, Gustavo Sosa Macias, R. Lee Reinhardt, J. Todd Purves, Jianxuan Wu, Soman N. Abraham, Hae Woong Choi
Publikováno v:
Nature immunology
Urinary tract infections (UTIs) typically evoke prompt and vigorous innate bladder immune responses, including extensive exfoliation of the epithelium. To explain the basis for the extraordinarily high recurrence rates of UTIs, we examined adaptive i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20c31e672be3c6e4026a98182c0d9b9
https://doi.org/10.1038/s41590-020-0688-3
https://doi.org/10.1038/s41590-020-0688-3
Autor:
Thomas Danhorn, James P. Scott-Browne, Max A. Seibold, Rachel A. Woolaver, R. Lee Reinhardt, Harsha Krovi, Mindy M. Miller, Laurent Gapin, Brian Vestal, Clemencia Pinilla, Cydney Rios, Brian P. O'Connor, Nathan Dyjack, Ivy K Brown, Ting-Hui Tu, Laura Harmacek, Radleigh Santos
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 6, p e1009602 (2021)
PLoS Pathogens, Vol 17, Iss 6, p e1009602 (2021)
The CD4+ T cell response is critical to host protection against helminth infection. How this response varies across different hosts and tissues remains an important gap in our understanding. Using IL-4-reporter mice to identify responding CD4+ T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965d2a8aa517c7889b852fbbf5ac5d18
http://europepmc.org/articles/PMC8216541
http://europepmc.org/articles/PMC8216541
Publikováno v:
Proc Natl Acad Sci U S A
Given the high frequency of urinary tract infections (UTIs) and their recurrence, there is keen interest in developing effective UTI vaccines. Currently, most vaccine studies, including those in humans, involve parenteral vaccination aimed at evoking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693ce28452f9919388212177ebaaed0e
https://doi.org/10.1073/pnas.2026461118
https://doi.org/10.1073/pnas.2026461118
Autor:
Mindy M. Miller, R. Lee Reinhardt
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
Soil-transmitted helminths represent a major global health burden with infections and infection-related comorbidities causing significant reductions in the quality of life for individuals living in endemic areas. Repeated infections and chronic colon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fff1ea5ce9b3fcf998e72495c253c3f
http://europepmc.org/articles/PMC7390839
http://europepmc.org/articles/PMC7390839
Autor:
Preeyam S. Patel, Brian P. O'Connor, R. Lee Reinhardt, Thomas Danhorn, Mindy M. Miller, Katherine Bao
Publikováno v:
Sci Immunol
A transitory, interleukin-25 (IL-25)-responsive, group 2 innate lymphoid cell (ILC2) subset induced during type 2 inflammation was recently identified as iILC2s. This study focuses on understanding the significance of this population in relation to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903db9c73d2ae6df1f13d3f777539bd6
https://doi.org/10.1126/sciimmunol.aay3994
https://doi.org/10.1126/sciimmunol.aay3994
Autor:
R. Lee Reinhardt, Mark Dell'Aringa
Publikováno v:
Mucosal immunology
Type-2 immunity is regulated by two distinct CD4+ T cell subsets. T follicular helper (Tfh) cells are required for humoral hallmarks of type-2 inflammation. T helper type-2 (Th2) cells orchestrate type-2 inflammation in peripheral tissues, such as th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41bffbba507c94ac6fc656b5833f08b5
https://doi.org/10.1038/s41385-018-0012-9
https://doi.org/10.1038/s41385-018-0012-9
Autor:
Maria Ciofani, William E. Barclay, R. Lee Reinhardt, Tiffany Carr, Jianxuan Wu, Jingxiao Jin, Katherine Bao
Publikováno v:
The Journal of Immunology. 197:4371-4381
The AP-1 factor basic leucine zipper transcription factor, ATF-like (BATF) is important for CD4+ Th17, Th9, and follicular Th cell development. However, its precise role in Th2 differentiation and function remains unclear, and the requirement for BAT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b7064555bfb2843ad0edcbf4bc00a4
https://doi.org/10.4049/jimmunol.1601371
https://doi.org/10.4049/jimmunol.1601371