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pro vyhledávání: '"R L Zastawny"'
Publikováno v:
British Journal of Cancer
A paucity of information exists on the regulation of gene expression in the undifferentiated intestine. The intestinal epithelium is one of the few normal tissues expressing the multidrug resistance (MDR) genes that confer the multidrug resistant phe
Autor:
Frank Merante, R.A. Janeczko, S. Bortolin, Peter V. Riccelli, Albert S. Benight, K. T. Leung, R. L. Zastawny
A microtiter-based assay system is described in which DNA hairpin probes with dangling ends and single-stranded, linear DNA probes were immobilized and compared based on their ability to capture single-strand target DNA. Hairpin probes consisted of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aaed3f0bc500c9f67eb1915604a5748
https://europepmc.org/articles/PMC29612/
https://europepmc.org/articles/PMC29612/
Publikováno v:
Oncogene. 8(6)
The overexpression of P-glycoprotein is thought to be responsible for resistance to chemotherapy in some non-responsive cancers. The mechanism by which P-glycoprotein is overexpressed in human tumors is poorly understood. However, several lines of ev
Publikováno v:
Molecular and Cellular Biology. 9:1224-1232
Overproduction of P-glycoprotein is intimately associated with multidrug resistance. This protein appears to be encoded by a multigene family. Thus, differential expression of different members of this family may contribute to the complexity of the m