Zobrazeno 1 - 10
of 10
pro vyhledávání: '"R L Shattuck"'
Autor:
D M Watterson, L J Van Eldik, P E Matrisian, Thomas J. Lukas, R L Shattuck, Warren E. Zimmer, M Collinge
Publikováno v:
Scopus-Elsevier
We have determined the first genomic structure and characterized the mRNA and protein products of a novel vertebrate gene that encodes a calcium-binding protein with amino acid sequence identity to a protein kinase domain. The elucidation of the comp
Autor:
R L Shattuck, D M Watterson, L J Van Eldik, Thomas J. Lukas, W. Lau, M.O. Shoemaker, Emily Wilson, L. Guerra-Santos, A P Kwiatkowski, P E Matrisian
Publikováno v:
The Journal of Cell Biology
Scopus-Elsevier
Scopus-Elsevier
The first primary structure for a nonmuscle myosin light chain kinase (nmMLCK) has been determined by elucidation of the cDNA sequence encoding the protein kinase from chicken embryo fibroblasts, and insight into the molecular mechanism of calmodulin
Publikováno v:
Molecular carcinogenesis. 24(3)
Both the matrix metalloproteinase matrilysin and the prostaglandin H synthase cyclooxygenase-2 (Cox-2), are thought to play key roles in colorectal carcinogenesis. These enzymes are overexpressed in 85-90% of human colorectal cancers. Furthermore, mi
Autor:
R L, Shattuck-Brandt, A, Richmond
Publikováno v:
Cancer research. 57(14)
The expression of the CXC chemokine MGSA is often deregulated during viral infection, chronic inflammation, and melanoma tumor progression. In Hs294T melanoma cells, the increased constitutive expression of MGSA is due to increased gene transcription
Publikováno v:
Molecular and cellular biology. 14(1)
We have characterized constitutive and cytokine-regulated MGSA/GRO alpha, -beta, and -gamma gene expression in normal retinal pigment epithelial (RPE) cells and a malignant melanoma cell line (Hs294T) to discern the mechanism for MGSA/GRO constitutiv
Publikováno v:
Oncogene. 6(7)
In the work described here we demonstrate that the clonal cell line Mel-a-6, produced by transfection of mouse Melan-a cells with human MGSA, had an increased ability to form large colonies in soft agar and increased ability to form tumors when injec
Publikováno v:
Molecular pharmacology. 31(5)
Bordetella pertussis, the pathogen responsible for whooping cough, releases a soluble calmodulin-sensitive adenylate cyclase into its culture medium which enters several different types of animal cells and elevates intracellular cAMP. In this study,
Publikováno v:
The Journal of biological chemistry. 263(14)
Bordetella pertussis, the etiologic agent of whooping cough, produces a calmodulin-sensitive adenylate cyclase which elevates intracellular cAMP in a variety of eucaryotic cells. Exogenous calmodulin added to the partially purified adenylate cyclase
Autor:
R L Shattuck, M.O. Shoemaker, Thomas J. Lukas, D M Watterson, W. Lau, Warren E. Zimmer, J. Haiech, T. A. Craig
Publikováno v:
Scopus-Elsevier