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Molecular basis for the regulation of islet beta cell mass in mice: the role of E-cadherin

Autor: R. L. Leibel, K. Watanabe, Paolo Meda, S. Xuan, N. Wakae-Takada

Publikováno v: Diabetologia
Diabetologia; Vol 56

In rodents and humans, the rate of beta cell proliferation declines rapidly after birth; formation of the islets of Langerhans begins perinatally and continues after birth. Here, we tested the hypothesis that increasing levels of E-cadherin during is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045ee780c44e751140d04ce94383aa43
https://doi.org/10.1007/s00125-012-2824-6

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Akademický článek

Radioisotopic method for the measurement of lipolysis in small samples of human adipose tissue.

Autor: R L Leibel, J Hirsch, E M Berry, R K Gruen

Publikováno v: Journal of Lipid Research, Vol 25, Iss 1, Pp 49-57 (1984)

To facilitate the study of adrenoreceptor response in small needle biopsy samples of human subcutaneous adipose tissue, we developed a dual radioisotopic technique for measuring lipolysis rate. Aliquots (20-75 mg) of adipose tissue fragments were inc

Externí odkaz: https://doaj.org/article/b383b9f9fff44e21aa72370e9aa87a24

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Adipositas – Basis-BMI für langfristigen Erfolg entscheidend

Autor: E Ferrannini, V Haas, R L Leibel, M Rosenbaum, G F Cahill

Publikováno v: Aktuelle Ernährungsmedizin. 40:60-61

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9585276939ba7e7997f08ca58575154
https://doi.org/10.1055/s-0034-1369727

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Phenotype of the obese Koletsky (f) rat due to Tyr763Stop mutation in the extracellular domain of the leptin receptor (Lepr): evidence for deficient plasma-to-CSF transport of leptin in both the Zucker and Koletsky obese rat

Autor: X. S. Wu-Peng, S. C. Chua, N. Okada, S. M. Liu, M. Nicolson, R. L. Leibel

Publikováno v: Diabetes. 46:513-518

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7fc325476e04e0df71dd7baa951dc514
https://doi.org/10.2337/diabetes.46.3.513

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Akademický článek

CD9 Counteracts Liver Steatosis and Mediates GCGR Agonist Hepatic Effects.

Autor: Zheng, Yi¹ (AUTHOR) cecilia.zy@163.com, Wang, Yuren¹ (AUTHOR), Xiong, Xin¹ (AUTHOR), Zhang, Linlin¹ (AUTHOR), Zhu, Jiaran¹ (AUTHOR), Huang, Bangliang¹ (AUTHOR), Liu, Xiufei¹ (AUTHOR), Liu, Jinbo² (AUTHOR), Zhu, Zhiming³ (AUTHOR), Yang, Gangyi⁴ (AUTHOR), Qu, Hua¹ (AUTHOR) quhuahua120@163.com, Zheng, Hongting¹ (AUTHOR) fnf7703@hotmail.com

Publikováno v: Advanced Science. 8/7/2024, Vol. 11 Issue 29, p1-15. 15p.

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Panel discussion: early nutrition in adult disease prevention

Autor: P O, Kwiterovich, J, Ingelfinger, R L, Leibel, R M, Lauer, C, Olson

Publikováno v: Bulletin of the New York Academy of Medicine. 65(10)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::389dfb73675ca2eb25f49ed47c26f5f2
https://pubmed.ncbi.nlm.nih.gov/19313079

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Calorie restriction and iopanoic acid effects on thyroid hormone metabolism

Autor: E Presta, M U Yang, H L Katzeff, T B Van Itallie, J Hirsch, R L Leibel

Publikováno v: The American Journal of Clinical Nutrition. 52:263-266

We measured the effects of iopanoic acid on thyroid hormone metabolism in obese men during severe calorie restriction to study the nutrition regulation of thyroid hormone metabolism. Eight morbidly obese men received a weight-maintenance diet followe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3790d07759fc08483180999dfd706a85
https://doi.org/10.1093/ajcn/52.2.263

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Akademický článek

Weight History Correlates of Resting Energy Expenditure in Women With Bulimia Nervosa.

Autor: Singh S; Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, USA.; Department of Psychological and Brain Sciences, Drexel University, Philadelphia, USA., Mayer L; Department of Psychiatry, Columbia University Irving Medical Center, New York City, USA., Rosenbaum M; Department of Pediatrics, Columbia University Irving Medical Center, New York City, USA.; Columbia University Clinical and Translational Science Award Program, New York City, USA., Lowe MR; Department of Psychological and Brain Sciences, Drexel University, Philadelphia, USA.

Publikováno v: The International journal of eating disorders [Int J Eat Disord] 2024 Sep; Vol. 57 (9), pp. 1899-1910. Date of Electronic Publication: 2024 Jul 01.

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The physiology of body weight regulation: relevance to the etiology of obesity in children

Autor: M, Rosenbaum, R L, Leibel

Publikováno v: Pediatrics. 101(3 Pt 2)

The prevalence of obesity in children and adults in the United States has increased by more than 30% over the past decade. Recent studies of the physiology and molecular genetics of obesity in humans have provided evidence that body weight (fat) is r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bf14b74b009aa863dbcb50afbef31890
https://pubmed.ncbi.nlm.nih.gov/12224659

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Leptin regulation of Agrp and Npy mRNA in the rat hypothalamus

Autor: J, Korner, E, Savontaus, S C, Chua, R L, Leibel, S L, Wardlaw

Publikováno v: Journal of neuroendocrinology. 13(11)

Agouti-related protein (AGRP) is synthesized in the same neurones in the arcuate nucleus as neuropeptide Y (NPY), another potent orexigenic peptide. AGRP antagonizes the action of alpha-melanocyte stimulating hormone, a derivative of pro-opiomelanoco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a9a895d4400dab04c48fa1723cc37026
https://pubmed.ncbi.nlm.nih.gov/11737554

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