Zobrazeno 1 - 10 of 26 pro vyhledávání: '"R L Gingerich"'
1
Des-(27-31)C-Peptide
Autor: Keith Rose, Philippe A. Halban, Marguerite Neerman-Arbez, C. B. Verchere, Steven E. Kahn, Jean-Claude Irminger, M. Paoletta, R. L. Gingerich
Publikováno v: Journal of Biological Chemistry. 271:27475-27481
Insulin and connecting peptide (C-peptide) are produced in equimolar amounts during proinsulin conversion in the pancreatic beta cell secretory granule. To determine whether insulin and C-peptide are equally stable in beta cell granules (and thus sec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7f87c372d412a9d2168c37534873aa68
https://doi.org/10.1074/jbc.271.44.27475
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2
Pancreatic polypeptide administration improves abnormal glucose metabolism in patients with chronic pancreatitis
Autor: R E Chance, D Elahi, Neal E. Seymour, A S Ryan, F C Brunicardi, Harold E. Lebovitz, Rochelle L Chaiken, Jules A. Hoffmann, Dana K. Andersen, R L Gingerich
Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 81:3566-3572
Chronic pancreatitis (CP) is associated with lowered plasma levels and a blunted nutrient-induced release of pancreatic polypeptide (PP). To investigate the possible role of PP on glucose metabolism, we studied male patients with documented CP (n = 5
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a7ca2fab07b8c8c5d9a3532f38a7cc
https://doi.org/10.1210/jcem.81.10.8855802
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5
Radioimmunoassay of rat leptin: sexual dimorphism reversed from humans
Autor: M, Landt, R L, Gingerich, P J, Havel, W M, Mueller, B, Schoner, J E, Hale, M L, Heiman
Publikováno v: Clinical chemistry. 44(3)
Adipose tissue secretes leptin, which interacts with receptors in the hypothalamus. In rodent models of obesity, leptin increases metabolism and decreases food intake, which helps to maintain normal body composition. Accurate and precise methods to q
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::96f713bd21408f2d475e9d2872ea937b
https://pubmed.ncbi.nlm.nih.gov/9510863
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6
Sexual dimorphism in plasma leptin concentration
Autor: M F, Saad, S, Damani, R L, Gingerich, M G, Riad-Gabriel, A, Khan, R, Boyadjian, S D, Jinagouda, K, el-Tawil, R K, Rude, V, Kamdar
Publikováno v: The Journal of clinical endocrinology and metabolism. 82(2)
Leptin, the obese (ob) gene product, is thought to be a lipostatic hormone that contributes to body weight regulation through modulating feeding behavior and/or energy expenditure. The determinants of plasma leptin concentration were evaluated in 267
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f8b9ac56982bdaefe30f3e467617d6f3
https://pubmed.ncbi.nlm.nih.gov/9024258
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7
Leptin concentrations in relation to overall adiposity and regional body fat distribution in Mexican Americans
Autor: S M, Haffner, R L, Gingerich, H, Miettinen, M P, Stern
Publikováno v: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. 20(10)
Leptin, the product of the human OB gene is increased in obese individuals suggesting resistance to its effect. However, there is variability in leptin levels at each level of body mass index suggesting that genetic and environmental factors other th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4cb5071bd4bd718ff918d58b1b7c6b61
https://pubmed.ncbi.nlm.nih.gov/8910093
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8
Radioimmunoassay of leptin in human plasma
Autor: Z, Ma, R L, Gingerich, J V, Santiago, S, Klein, C H, Smith, M, Landt
Publikováno v: Clinical chemistry. 42(6 Pt 1)
Recent studies suggest that leptin, the ob gene product absent in ob/ob mice, is a negative regulator of adiposity. We developed an RIA to measure human leptin in plasma or serum. The minimum detectable concentration by the assay is 0.5 microg/L lept
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f01ff72bf47f7c2494f90788be592f4e
https://pubmed.ncbi.nlm.nih.gov/8665672
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9
Des-(27-31)C-peptide. A novel secretory product of the rat pancreatic beta cell produced by truncation of proinsulin connecting peptide in secretory granules
Autor: C B, Verchere, M, Paoletta, M, Neerman-Arbez, K, Rose, J C, Irminger, R L, Gingerich, S E, Kahn, P A, Halban
Publikováno v: Journal of Biological Chemistry, Vol. 271, No 44 (1996) pp. 27475-27481
Insulin and connecting peptide (C-peptide) are produced in equimolar amounts during proinsulin conversion in the pancreatic beta cell secretory granule. To determine whether insulin and C-peptide are equally stable in beta cell granules (and thus sec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::edcbec68e120dd54a713cbe97a3f161f
https://archive-ouverte.unige.ch/unige:9075
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10
Parathyroid hormone decreases in vivo insulin effect on glucose utilization
Autor: A. W. Saxe, R. L. Gingerich, Glenn Gibson, J. Levy
Publikováno v: Calcified tissue international. 57(2)
Hyperparathyroidism is associated with impaired glucose tolerance, and parathyroidectomy may improve carbohydrate homeostasis. It has been suggested that parathyroid hormone (PTH) suppresses insulin secretion but it is unclear whether it also interfe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b95b374d05d0b5c9292f4abf050a70
https://pubmed.ncbi.nlm.nih.gov/7584873
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