Výsledky vyhledávání

The balance between immunity and tolerance: The role of Langerhans cells

Autor: C. L. Berger, R. L. Edelson, K. Mutyambizi

Langerhans cells are immature skin-homing dendritic cells that furnish the epidermis with an immune surveillance system, and translate information between the internal and external milieu. Dendritic cells, in particular Langerhans cells, are gaining

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c4e3acf7ba506517e7366184b105a2
https://europepmc.org/articles/PMC4075167/

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Cutaneous T cell lymphoma: translating immunobiology into therapeutic opportunities

Autor: C L, Berger, P, Heald, M, Girardi, R L, Edelson

Publikováno v: Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia. 143(1)

Cutaneous T cell lymphoma (CTCL) has always served as a proving ground where conceptual advances in immunology can be tested and the results translated into clinical practice. From the earliest studies that used sheep red blood cells to identify the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::12ccf9b60c41c11b07361fc478db65a0
https://pubmed.ncbi.nlm.nih.gov/18833050

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Cutaneous T cell lymphoma: the helping hand of dendritic cells

Autor: R L, Edelson

Publikováno v: Annals of the New York Academy of Sciences. 941

Since its introduction 25 years ago, cutaneous T cell lymphoma has become the preferred designation for clonal malignancies of those CD4 thymus-derived lymphocytes ("cutaneous T cells") that preferentially migrate to skin. The varied cutaneous clinic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::be33e6befb03b813e27906a31e3ea139
https://pubmed.ncbi.nlm.nih.gov/11594563

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Induction of human tumor-loaded dendritic cells

Autor: C L, Berger, A L, Xu, D, Hanlon, C, Lee, J, Schechner, E, Glusac, I, Christensen, E, Snyder, V, Holloway, R, Tigelaar, R L, Edelson

Publikováno v: International journal of cancer. 91(4)

A preferred anti-cancer vaccine would be tumor-specific, simple to rapidly construct and safe to administer. It would permit immunization against a spectrum of the tumor's distinctive antigens, without requiring their prior identification. Toward the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d06cac0c4e9b36ad2e690c1575929d47
https://pubmed.ncbi.nlm.nih.gov/11251964

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P-glycoprotein expression and multidrug resistance in cutaneous T-cell lymphoma

Autor: B J Longley, J R Murren, D L Cooper, A P Jillella, K K Hamid, R L Edelson

Publikováno v: Cancer investigation. 18(7)

Advanced-stage cutaneous T-cell lymphoma (CTCL) is generally resistant to standard chemotherapy. Because P-glycoprotein (P-gp) has been detected in other types of resistant solid tumors, leukemias, and lymphomas, we analyzed P-gp expression in CTCL.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3efe26bd1b6707bd7ea07cf5b1ac69e7
https://pubmed.ncbi.nlm.nih.gov/11036468

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Cutaneous T-cell lymphoma: pathogenesis and treatment

Autor: M, Girardi, R L, Edelson

Publikováno v: Oncology (Williston Park, N.Y.). 14(7)

Cutaneous T-cell lymphoma (CTCL) is a malignancy of a distinctive subset of T-helper cells designated "cutaneous T cells" because of their central role in the normal functioning of the skin immune system. Guided by selective adhesion molecules, activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1f13107a552aec066add2e6ec2fe558f
https://pubmed.ncbi.nlm.nih.gov/10929591

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Integrins alpha4beta7 and alphaEbeta7 are expressed on epidermotropic T cells in cutaneous T cell lymphoma and spongiotic dermatitis

Autor: J S, Schechner, R L, Edelson, J M, McNiff, P W, Heald, J S, Pober

Publikováno v: Laboratory investigation; a journal of technical methods and pathology. 79(5)

Integrin alpha4beta7 has been associated with tissue-specific homing of malignant and inflammatory lymphocytes to gastrointestinal mucosa, whereas integrin alphaEbeta7 has been associated with intraepithelial lymphocytes in both the gut and the skin.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8ab0c51c88b8be9518a82500c8ef9976
https://pubmed.ncbi.nlm.nih.gov/10334571

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