Zobrazeno 1 - 10
of 15
pro vyhledávání: '"R L Deem"'
Publikováno v:
The Journal of Immunology. 159:6276-6282
Recent clinical studies of Crohn's disease patients demonstrated dramatic clinical responses following one i.v. infusion of a chimeric mAb to TNF-alpha (cA2). To assess the role of TNF-alpha in mucosal cytokine regulation, the effects of TNF-alpha on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21971026521fa1c23f2eb7631af72f65
https://doi.org/10.4049/jimmunol.159.12.6276
https://doi.org/10.4049/jimmunol.159.12.6276
Publikováno v:
The Journal of Immunology. 154:664-675
This study was designed to compare cytokine release in lamina propria lymphocytes (LPLs) and PBLs activated by Abs against CD3, CD2, and CD28. LPL T cells were significantly more responsive to CD2 ligation than PBL, as determined by release of IFN-ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be1695e2f412820c3a09116439b1d300
https://doi.org/10.4049/jimmunol.154.2.664
https://doi.org/10.4049/jimmunol.154.2.664
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(11)
The pathways leading to activation in lamina propria (LP) T cells are different from peripheral T cells. LP T cells exhibit enhanced IL-2 secretion when activated through the CD2 pathway. Coligation of CD28 leads to synergistic enhancement of IL-2 se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13ed88897e52f4cff0be823837a258c3
https://pubmed.ncbi.nlm.nih.gov/10352279
https://pubmed.ncbi.nlm.nih.gov/10352279
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(10)
The aim of this study was to identify molecular mechanisms involved in transcriptional regulation of IL-2 expression following CD2 and CD3 activation in lamina propria (LP) T cells. Studies used T cells from normal, ulcerative colitis, and Crohn's di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3460ca59d9592712515fb476473ac4b9
https://pubmed.ncbi.nlm.nih.gov/9590239
https://pubmed.ncbi.nlm.nih.gov/9590239
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(12)
Recent clinical studies of Crohn's disease patients demonstrated dramatic clinical responses following one i.v. infusion of a chimeric mAb to TNF-alpha (cA2). To assess the role of TNF-alpha in mucosal cytokine regulation, the effects of TNF-alpha on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3da032bdf54e54eedb6c8f1c59aaeba1
https://pubmed.ncbi.nlm.nih.gov/9550432
https://pubmed.ncbi.nlm.nih.gov/9550432
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 154(2)
This study was designed to compare cytokine release in lamina propria lymphocytes (LPLs) and PBLs activated by Abs against CD3, CD2, and CD28. LPL T cells were significantly more responsive to CD2 ligation than PBL, as determined by release of IFN-ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::36af6826167585d7a6ed9ed15eeee3ac
https://pubmed.ncbi.nlm.nih.gov/7529282
https://pubmed.ncbi.nlm.nih.gov/7529282
Autor:
R L Deem, S R Targan
Publikováno v:
The Journal of Immunology. 133:1836-1840
The substages of natural killer cell-derived cytolytic factor (NKCF)-mediated cytolysis have been examined by using the bifunctional protein cross-linking reagent glutaraldehyde. Glutaraldehyde (2 X 10(-4%)) enhanced both the level and rate of lysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ecd9dc55f3bc1e573a02775128f468f
https://doi.org/10.4049/jimmunol.133.4.1836
https://doi.org/10.4049/jimmunol.133.4.1836
Publikováno v:
The Journal of Immunology. 130:2401-2406
Macrophage-depleted populations of splenic lymphocytes obtained from immunized and nonimmunized BALB/c mice were tested to determine their ability to kill Nocardia asteroides GUH-2 in vitro. Nocardia-primed lymphocytes, but not normal lymphocytes, ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81b4bad880779a8dbe6f9aea78d56ff6
https://doi.org/10.4049/jimmunol.130.5.2401
https://doi.org/10.4049/jimmunol.130.5.2401
Autor:
R L Deem, S R Targan
Publikováno v:
The Journal of Immunology. 133:72-77
The role of membrane movement during the stages of human NK cytolysis has been examined by using the bifunctional protein cross-linking reagent, glutaraldehyde. The binding stage was inhibited when K562 target cells or NK cells were pretreated with g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb6740ccf5b06365b54e2658bee6e6b3
https://doi.org/10.4049/jimmunol.133.1.72
https://doi.org/10.4049/jimmunol.133.1.72
Publikováno v:
Infection and Immunity. 38:914-920
Nude mice on a BALB/c background were adoptively transferred with unprimed spleen cells, Nocardia-primed spleen cells, or Nocardia-primed splenic T lymphocytes from syngeneic, heterozygous (nu/+) littermates. Two days later, these recipient mice and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89df605c1d2c1d205a565af91c075199
https://doi.org/10.1128/iai.38.3.914-920.1982
https://doi.org/10.1128/iai.38.3.914-920.1982