Zobrazeno 1 - 10
of 63
pro vyhledávání: '"R L Brinster"'
Publikováno v:
Mouse genome. 87
Autor:
B P, Zambrowicz, J W, Zimmermann, C J, Harendza, E M, Simpson, D C, Page, R L, Brinster, R D, Palmiter
Publikováno v:
Development. 120:1549-1559
The Zfy-1 and Zfy-2 genes, which arose by gene duplication, map to the mouse Y chromosome and encode nearly identical zinc-finger proteins. Zfy-1 is expressed in the genital ridge and adult testis and likely encodes a transcription activator. Althoug
Publikováno v:
The Journal of Immunology. 151:3954-3960
A variety of cell types expressing MHC class II molecules is known to function as APC in vitro. We employed the Ig kappa gene enhancer and promoter to target the class II E alpha gene, and thereby I-E, exclusively to B cells to address their APC func
Publikováno v:
Biology of reproduction. 64(5)
In mice, transplantation of spermatogonial stem cells from a fertile male to the seminiferous tubules of an infertile recipient male results in progeny with donor-derived haplotype. Attempts to extend this approach by transplanting human testis cells
Publikováno v:
Biology of reproduction. 61(5)
Spermatogonial stem cells of a fertile mouse transplanted into the seminiferous tubules of an infertile mouse can develop spermatogenesis and transmit the donor haplotype to progeny of the recipient mouse. When testis cells from rats or hamsters were
Publikováno v:
Molecular reproduction and development. 53(2)
Transplantation of spermatogonial stem cells from fertile, transgenic donor mice to the testes of infertile recipients provides a unique system to study the biology of spermatogonial stem cells. To facilitate the investigation of treatment effects on
Publikováno v:
Biology of reproduction. 60(6)
Recently a system was developed in which transplanted donor spermatogonial stem cells establish complete spermatogenesis in the testes of an infertile recipient. To obtain insight into stem cell activity and the behavior of donor germ cells, the patt
Publikováno v:
Biology of reproduction. 60(2)
It was recently demonstrated that rat spermatogenesis can occur in the seminiferous tubules of an immunodeficient recipient mouse after transplantation of testis cells from a donor rat. In the present study, hamster donor testis cells were transplant
Publikováno v:
Biology of reproduction. 59(6)
Spermatogenesis is one of the most productive self-renewing systems in the body: on the order of 10(7) spermatozoa are produced daily per gram of testis tissue. In each mammalian species, the time required for completion of the process is unique and
Publikováno v:
Biology of reproduction. 59(6)
Development of spermatogonial transplants was studied by using 5- to 6-wk-old histocompatible mice as cell donors and sterile (W-locus) mice as recipients. Groups of animals transplanted with germ cell suspensions were killed at 10 min, 9 h, 24 h, 1