Zobrazeno 1 - 10
of 62
pro vyhledávání: '"R L Bowen"'
Autor:
Jane Warwick, P Quinlan, William J. Tapper, Diana Eccles, Lee B. Jordan, P Chou, C Gillet, Antonio Saha, Shelia M. Violette, Jane Kendrew, AM Thompson, Stephen W. Duffy, R L Bowen, Andrew R. Green, Simon T. Barry, A Brentall, Rhian Gabe, Ian O. Ellis, Kate Moore, John Marshall, Ian R. Hart, S. Vallath, Kellie Brouilette, Gareth J. Thomas, JL Jones, Claude Chelala, Syed Haider, Paul H. Weinreb
Publikováno v:
Cancer Research. 73:P4-15
The integrin avβ6 promotes migration, invasion and survival of cancer cells, but the biological relevance has yet to be ascertained in breast cancer. Our immunhistochemical analysis of over 2000 breast cancers has revealed that high expression of th
Publikováno v:
Diagnostic Histopathology. 18:104-111
Basal-like breast cancers express genes and proteins associated with the basal layer of mammary epithelium and account for 10–25% of breast cancers. These tumours are of particular interest because they follow an aggressive clinical course and curr
Publikováno v:
British Journal of Cancer
Background: Molecular profiling has identified at least four subtypes of invasive breast carcinoma, which exhibit distinct clinical behaviour. There is good evidence now that DCIS represents the non-obligate precursor to invasive breast cancer and th
Autor:
Georgios Giamas, Paul J. Mintz, Louise J. Jones, Nagy A. Habib, Jacqueline S. Lewis, R. Charles Coombes, R L Bowen, Justin Stebbing
Publikováno v:
Cancer. 113:1489-1495
BACKGROUND Estrogens play a central role in breast cancer development, and the estrogen receptor-alpha (ERalpha) remains the single most important predictor of breast cancer prognosis. Therefore, it is crucial to elucidate pathways that may contribut
Publikováno v:
Histopathology. 52:82-90
Breast cancer is a heterogeneous disease and there is a continual drive to identify markers that will aid in predicting prognosis and response to therapy. To date, relatively few markers have established prognostic power. Oestrogen receptor (ER) is p
Autor:
C W Gregory, R L Bowen
Publikováno v:
CMLS Cellular and Molecular Life Sciences. 62:313-319
The relationship between hormones and Alzheimer's disease (AD) has been intensely researched. While the majority of this work has focused on the sex steroids, estrogens, and more recently androgens, a serendipitous patient encounter led one of us (R.
Autor:
Jeanine Albu, Richard L. Atkinson, Barbara A. Israel, David B. Allison, R L Bowen, A S Augustus, Nikhil V. Dhurandhar
Publikováno v:
International Journal of Obesity. 29:281-286
Human adenovirus-36 (Ad-36) increases adiposity and paradoxically lowers serum cholesterol and triglycerides in chickens, mice, and non-human primates. The role of Ad-36 in human obesity is unknown. To determine the prevalence of Ad-36 antibodies in
Autor:
Jane Kendrew, P Quinlan, Diana Eccles, Syed Haider, J. Louise Jones, Sabari Vallath, Ian R. Hart, Antonio Saha, Ian O. Ellis, Adam R. Brentnall, Andrew R. Green, Gareth J. Thomas, Rhian Gabe, Paul H. Weinreb, Lee B. Jordan, Jane Warwick, Patrick Chou, Cheryl Gillett, Simon T. Barry, Kellie Brouilette, Shelia M. Violette, William J. Tapper, John Marshall, Stephen W. Duffy, R L Bowen, Claude Chelala, Alastair M. Thompson, Kate Moore
Publikováno v:
JNCI Journal of the National Cancer Institute
BACKGROUND: Integrin ?v?6 promotes migration, invasion, and survival of cancer cells; however, the relevance and role of ?v?6 has yet to be elucidated in breast cancer.METHODS: Protein expression of integrin subunit beta6 (?6) was measured in breast
Publikováno v:
British medical bulletin. 103(1)
Background Breast cancer is a highly heterogeneous disease, but the stage at presentation significantly influences outcome. It is important to dissect the pathobiological and epidemiological factors that influence the stage at presentation in order t
Autor:
R. L. Bowen, W. A. Marjenhoff
Publikováno v:
Journal of Esthetic and Restorative Dentistry. 3:86-90
The development of an adhesion system for bonding dental composites to dentin and enamel is reviewed. Building on findings concerning adhesion to enamel, a field pioneered by Dr. Michael Buonocore and others, Dr. R.L. Bowen and his colleagues at the