Zobrazeno 1 - 7
of 7
pro vyhledávání: '"R L, Yung"'
Publikováno v:
The Journal of Immunology. 154:3025-3035
Treating activated CD4+ T cells with DNA methyltransferase inhibitors modifies gene expression and induces autoreactivity. Adoptive transfer of viable polyclonal autoreactive cells causes a lupus-like disease, most likely because of one or more effec
Autor:
R L, Yung
Publikováno v:
Current opinion in investigational drugs (London, England : 2000). 2(2)
Immunex has developed and launched etanercept, a soluble TNF receptor (TNFR) fusion protein, for the treatment of early and moderate to severely active rheumatoid arthritis (RA). Etanercept was launched as a first-line agent in the US for the treatme
Publikováno v:
Immunological investigations. 29(4)
Overexpressing LFA-1 (CD11a/CD18) on antigen specific CD4+ T cells makes the cells proliferate to normally subthreshold stimuli, including self-Ia molecules without specific antigen. The mechanisms by which this occurs are unknown, but potentially in
Autor:
R L, Yung
Publikováno v:
Clinical and experimental rheumatology. 17(3)
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 73(6)
Although the importance of DNA methylation in normal cellular development and hereditary disease states has been appreciated for some time, the role of environmental agents in causing DNA methylation abnormalities and the effects of DNA hypomethylati
Autor:
R L, Yung, B C, Richardson
Publikováno v:
Rheumatic diseases clinics of North America. 20(1)
Recent years have seen promising developments in both our appreciation of the spectrum of autoimmune phenomena associated with DIL as well as our understanding of the pathogenesis of this disease. From our present knowledge, it seems likely that the
Publikováno v:
Journal of Clinical Oncology. 27:11051-11051
11051 Background: Information on the characteristics of cancer in people ≥ 85 is limited, particularly in men. Methods: We evaluated the type, grade and extent of cancer among the 22,071 men in the Physicians’ Health Study by age at diagnosis (dx