Zobrazeno 1 - 10
of 17
pro vyhledávání: '"R L, Wolfert"'
Publikováno v:
Clinical Chemistry. 38:2318-2321
We developed a panel of monoclonal antibodies to human bone gla protein (BGP; osteocalcin) peptides that span the linear sequence of the molecule, specifically BGP 1-12 (N-terminal), BGP 15-30 (midregion), and BGP 38-49 (C-terminal). These antibodies
Generation of PSA-ACT-specific monoclonal antibodies and their application in a sandwich immunoassay
Autor:
T J, Wang, H J, Linton, J, Payne, H G, Rittenhouse, D W, Chan, A W, Partin, R L, Wolfert, K, Kuus-Reichel
Publikováno v:
Hybridoma. 18(6)
The prostate-specific antigen (PSA) immunoassay is an important tool for the detection and monitoring of prostate cancer. PSA exists in serum mainly as complexes with serine protease inhibitors including alpha1 antichymotrypsin (ACT) and alpha2 macro
Autor:
S D, Mikolajczyk, L S, Millar, K M, Marker, H G, Rittenhouse, R L, Wolfert, L S, Marks, M C, Charlesworth, D J, Tindall
Publikováno v:
Cancer research. 59(16)
Human kallikrein (hK) 2 is an arginine-selective serine protease expressed predominantly in the prostate that has an 80% sequence identity with prostate-specific antigen. Expression of hK2 is elevated in the tumor epithelium compared to benign prosta
Publikováno v:
Cancer research. 58(21)
An alternatively spliced variant of prostate-specific membrane antigen (PSMA) designated PSM' was originally described following identification of its mRNA in normal prostate. We have purified the PSM' protein from LNCaP cells using two immunoaffinit
Autor:
M S, Saedi, T M, Hill, K, Kuus-Reichel, A, Kumar, J, Payne, S D, Mikolajczyk, R L, Wolfert, H G, Rittenhouse
Publikováno v:
Clinical chemistry. 44(10)
Prostate-specific antigen (PSA, hK3) is a diagnostic marker for prostatic cancer but lacks the specificity to sufficiently distinguish between prostatic cancer and benign prostatic hyperplasia (BPH). Human glandular kallikrein 2 (hK2) has been propos
Publikováno v:
Journal of andrology. 19(4)
Forms of human glandular kallikrein (kK2) in prostate carcinoma serum were identified using monoclonal antibodies specific for hK2 and prohK2. Recombinant mammalian hK2, prohK2, and prostate = specific antigen (PSA) were utilized to confirm the speci
Publikováno v:
Clinical chemistry. 44(4)
Autor:
G P, Murphy, M J, Troychak, O E, Cobb, V A, Bowes, R J, Kenny, R J, Barren, G M, Kenny, H, Ragde, E H, Holmes, R L, Wolfert
Publikováno v:
The Prostate. 33(2)
Metastatic prostate cancer clinical evaluation is difficult. A revaluation of new prostate markers with regard to bone scans was performed.Serial markers, including bone alkaline phosphatase (BAP), total alkaline phosphatase (TAP), prostate-specific
Publikováno v:
The Prostate. 28(1)
Prostate-specific antigen (PSA) is the most important tumor marker for early detection and monitoring of prostate cancer (PCa) patients. PSA is also elevated in many patients with benign prostatic hyperplasia (BPH). The study of the serum PSA forms,
Autor:
A W, Partin, S, Piantadosi, E N, Subong, C A, Kelly, S, Hortopan, D W, Chan, R L, Wolfert, H G, Rittenhouse, H B, Carter
Publikováno v:
The Prostate. Supplement. 7
Our objective was to determine the clearance rate of free and total serum PSA following radical retropubic prostatectomy.Sera were obtained from 10 men with localized prostate cancer prior to and 1, 4, 8, 24, 48, and 72 hr after radical prostatectomy