Zobrazeno 1 - 10
of 21
pro vyhledávání: '"R L, Silverstein"'
Publikováno v:
Blood. 87:2020-2028
CD36 is an 88-kD integral membrane glycoprotein expressed on monocytes, platelets, and certain microvascular endothelium serving distinct cellular functions both as an adhesive receptor for thrombospondin, collagen, and Plasmodium falciparum-infected
Publikováno v:
The Journal of Immunology. 154:4768-4777
Activated monocytes express tissue factor (TF), a protein that is important in the pathogenesis of thrombotic disorders. We sought to characterize an adhesion-dependent pathway for monocyte activation. In this study, we showed that adhesion of monocy
Autor:
A A, Timur, G, Murugesan, L, Zhang, P P, Aung, J, Barnard, Q K, Wang, P, Gaussem, R L, Silverstein, D L, Bhatt, K, Kottke-Marchant
Publikováno v:
International journal of laboratory hematology. 34(5)
Association of P2RY1 and P2RY12 polymorphisms with on-aspirin platelet reactivity was investigated.Platelet reactivity was assessed by the light transmission aggregometry and TxB(2) assay in 423 patients with coronary artery disease (CAD) on aspirin.
Publikováno v:
Molecular and cellular biochemistry. 239(1-2)
Fatty acid translocase (FAT)/CD36 has been associated with diverse normal and pathologic processes. These include scavenger receptor functions (uptake of apoptotic cells and modified lipid), lipid metabolism and fatty acid transport, adhesion, angiog
Autor:
M. L. Febbraio, E. Guy, C. Coburn, F. F. Knapp, A. L. Beets, N. A. Abumrad, R. L. Silverstein
Publikováno v:
Cellular Lipid Binding Proteins ISBN: 9781461348689
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db0bf3081dd19af9074c650ae594e49f
https://doi.org/10.1007/978-1-4419-9270-3_24
https://doi.org/10.1007/978-1-4419-9270-3_24
Publikováno v:
Annals of the New York Academy of Sciences. 902
CD36, an 88 kD transmembrane glycoprotein, is an important receptor for oxidized lipoproteins. Unlike the LDL receptor, expression of CD36 is upregulated by this pro-atherogenic particle, and binding and uptake perpetuates a cycle of lipid accumulati
Publikováno v:
Journal of lipid research. 41(5)
CD36, a class B scavenger receptor, is a macrophage receptor for oxidized low density lipoprotein (OxLDL) and may play a critical role in atherosclerotic foam cell formation. We have previously demonstrated that OxLDL, macrophage-colony stimulating f
Autor:
A J, Naiyer, D Y, Jo, J, Ahn, R, Mohle, M, Peichev, G, Lam, R L, Silverstein, M A, Moore, S, Rafii
Publikováno v:
Blood. 94(12)
Homing of hematopoietic stem cells to the bone marrow (BM) involves sequential interaction with adhesion molecules expressed on BM endothelium (BMEC) and chemokine stromal derived factor-1 (SDF-1). However, the mechanism whereby adhesion molecules re
Publikováno v:
Blood. 89(1)
We previously reported that monocyte adhesion to tumor necrosis factor-alpha (TNF-alpha)-treated endothelial cells increased expression of tissue factor and CD36 on monocytes. Using immunological cross-linking to mimic receptor engagement by natural
Autor:
A J, Marcus, L B, Safier, M J, Broekman, N, Islam, J H, Fliessbach, K A, Hajjar, W E, Kaminski, E, Jendraschak, R L, Silverstein, C, von Schacky
Publikováno v:
Thrombosis and haemostasis. 74(1)
Platelet activation as a result of vascular injury provokes endothelial cells to respond in a manner which limits or reverses the occlusive consequences of platelet accumulation. If the agonistic forces are strong, platelet accumulation is irreversib