Zobrazeno 1 - 10
of 21
pro vyhledávání: '"R L, Moldwin"'
Publikováno v:
Transfusion. 44:438-449
BACKGROUND: Hemangioblastic precursors have been identified that give rise to both endothelial cells and HPCs, suggesting that common growth factor requirements may exist. STUDY DESIGN AND METHODS: The effect of vascular endothelial growth factor (VE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0c38d557146713bce3cc9b0192d43ef
https://doi.org/10.1111/j.1537-2995.2003.00661.x
https://doi.org/10.1111/j.1537-2995.2003.00661.x
Autor:
A Harden, Janet D. Rowley, Nancy J. Zeleznik-Le, Y Suto, Stephen D. Smith, R. J. Allen, M M Le Beau, L Giordano, Christine Vignon, R. L. Moldwin, Thomas Ried, Richard A. Larson, M M Lu, Ronald J. Tomek, T Veldman
Publikováno v:
Scopus-Elsevier
A new cell line with megakaryoblastic features, designated UoC-M1, was established from the malignant cells of a 68-year-old patient with acute myeloid leukemia. The patient's leukemic cells reacted with alpha-naphthyl acetate esterase and acid phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940b073702ebba7f1a58bc0ca45508b9
https://doi.org/10.1038/sj.leu.2401002
https://doi.org/10.1038/sj.leu.2401002
Publikováno v:
Transfusion. 39(4)
BACKGROUND: The residual blood left in the placenta, previously considered a biologic waste, contains sufficient hematopoietic stem and progenitor cells to consistently engraft at least a small recipient. Over the past several years, more than 500 HL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0719c42893950c454b77fdc9a3cea59f
https://pubmed.ncbi.nlm.nih.gov/10220257
https://pubmed.ncbi.nlm.nih.gov/10220257
Autor:
R. L. Moldwin, R. J. Allen, P. J. Le Moine, N. H. Aithal, R. Gupta, Stephen D. Smith, P. A. Downie, A. Goldberg, D. H. Kim, L Giordano
Publikováno v:
Leukemia research. 21(10)
Leukemic cell lines have proven invaluable in the molecular analysis of recurring chromosomal translocations but the optimal methods for leukemia cell line establishment are unknown. During in vitro culture, most B-cell precursor acute lymphoblastic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d19bac97443647506ac08a2de9afd09
https://pubmed.ncbi.nlm.nih.gov/9403003
https://pubmed.ncbi.nlm.nih.gov/9403003
Autor:
D H, Kim, R L, Moldwin, C, Vignon, S K, Bohlander, Y, Suto, L, Giordano, R, Gupta, S, Fears, G, Nucifora, J D, Rowley
Publikováno v:
Blood. 88(3)
The t(12;21) (p 13; q22) results in the fusion of the TEL gene located on chromosome 12 with the AML1 gene located on the derivative chromosome 21. Because this translocation is difficult to detect using standard cytogenetic techniques, 27 previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::afdbf98ca32d5256824c2a05e53940d6
https://pubmed.ncbi.nlm.nih.gov/8704231
https://pubmed.ncbi.nlm.nih.gov/8704231
Publikováno v:
Leukemia. 10(4)
The CDKN2 gene has been recently localized to a chromosomal region found to be deleted in leukemias and solid tumors. CDKN2 encodes a 16 kDa protein product (p16INK4A), which functions as a specific inhibitor or the cyclin-dependent kinases 4 and 6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf32ad0e0e518b2b7fac4b0264b8a04a
https://pubmed.ncbi.nlm.nih.gov/8618438
https://pubmed.ncbi.nlm.nih.gov/8618438
Autor:
P A, Downie, N J, Vogelzang, R L, Moldwin, M M, Le Beau, J, Anastasi, R J, Allen, S E, Myers, R A, Larson, S D, Smith
Publikováno v:
Cancer research. 54(18)
We report the establishment of a leukemia cell line (UoC-B10) from a patient who developed leukemia several months after the diagnosis of a mediastinal yolk sac tumor. The patient's yolk sac tumor responded to combination chemotherapy, and a mature t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9dedb402b00b5252b127ee4f6128f9b
https://pubmed.ncbi.nlm.nih.gov/8069867
https://pubmed.ncbi.nlm.nih.gov/8069867
Publikováno v:
Experimental Hematology. 28:94
CD34+ cells that co-express KDR (a VEGF receptor) have been identified in umbilical cord blood (CB) and shown to be rich in primitive stem cell activity. We studied the production of CD34+KDR+ cells in stem cell “expansion” cultures. CD34+ cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dfc8891a8e6d4da60f6c08ba65f820b
https://doi.org/10.1016/s0301-472x(00)00381-7
https://doi.org/10.1016/s0301-472x(00)00381-7
Publikováno v:
The Journal of Experimental Medicine
Proliferation of T lymphocytes can be induced by IL-2, either through an autocrine pathway in which the responding cell produces its own IL-2 or through an exocrine pathway in which IL-2 secreted by Th stimulates proliferation of IL-2-dependent CTL.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ced23481c7bcd942449f45742c10273
https://doi.org/10.1084/jem.163.6.1566
https://doi.org/10.1084/jem.163.6.1566
Publikováno v:
Clinical Immunology and Immunopathology. 39:368-378
The effects of interleukin-2 (IL-2) on the expression of IL-2 receptors by cloned cytolytic and helper T lymphocytes were studied using three anti-IL-2 receptor antibodies. IL-2 enhanced the expression of IL-2 receptors on all clones tested. A steep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be56aec1d6adc8ba2b56d96485cf2066
https://doi.org/10.1016/0090-1229(86)90165-0
https://doi.org/10.1016/0090-1229(86)90165-0