Zobrazeno 1 - 10
of 38
pro vyhledávání: '"R L, Letsinger"'
Autor:
Ranajit Pal, M. G. Sarngadharan, O. Kinstler, R. L. Letsinger, George M. Hoke, A. L. Devico, S. Mumbauer, C. A. Stein
Publikováno v:
Biochemistry. 30:2439-2444
A phosphorothioate homocytidine 10-mer containing a cholesteryl moiety covalently linked to the 5'-end (Chol-SdC10) inhibited syncytium formation in susceptible T cells induced by HIV-1 and HIV-2. The syncytium inhibition effect was minimal with unmo
Autor:
R L, Letsinger
Publikováno v:
Nucleic acids symposium series. (29)
Publikováno v:
Nucleic acids symposium series. (24)
Phosphorothioate oligonucleotide analogs conjugated to cholesteryl by a neutral, 6 atom linker are more effective inhibitors of HIV-1 in cell culture than the corresponding analogs conjugated via a phosphorothioate group. The antiviral activity corre
Publikováno v:
Photochemistry and Photobiology. 17:295-301
— Quantum yields for 254 nm ultraviolet photoaddition of the nucleophiles hydrazine, HCN, HSO3-, methyl amine, and BH4- to uracil have been measured; the quantum yields for hydrazine, HCN, and HSO3- additions are pH-dependent. The nucleophiles sulf
Publikováno v:
The Journal of Organic Chemistry. 29:2615-2618
Publikováno v:
Journal of the American Chemical Society. 81:1965-1968
Publikováno v:
Journal of the American Chemical Society. 81:1068-1077
Autor:
R. L. Letsinger
Publikováno v:
Journal of the American Chemical Society. 70:406-409
Autor:
K. E. Steller, R. L. Letsinger
Publikováno v:
The Journal of Organic Chemistry. 35:308-313
Autor:
R. L. Letsinger, D. M. Jerina
Publikováno v:
Journal of Polymer Science Part A-1: Polymer Chemistry. 5:1977-1986
A study was made of the comparative rates of reaction of active ester functional groups (p-nitrophenyl and 2,4-dinitrophenyl esters) situated on three types of insoluble support polymers and on small, soluble analogs of the polymer molecules. The sup