Zobrazeno 1 - 10
of 18
pro vyhledávání: '"R L, Komaleva"'
Autor:
E. E. Petrova, O. A. Dmitrenko, A. V. Maerle, D. Yu. Trofimov, D. Yu. Ryazantsev, I. V. Sergeev, Sergey K. Zavriev, R. L. Komaleva
Publikováno v:
Russian Journal of Bioorganic Chemistry. 40:526-531
A highly sensitive test system, based on the immuno-PCR method, was developed for the detection of two staphylococcal toxins: enterotoxin A (SEA) and toxic shock syndrome toxin (TSST). A key element of the developed systems was to obtain supramolecul
Autor:
Tatiana M. Andronova, M. A. Simonova, Marina V. Britsina, Tatiana I. Valyakina, E. E. Petrova, V. A. Nesmeyanov, R. L. Komaleva
Publikováno v:
Biomedicine & Pharmacotherapy. 64:240-248
We have shown that glucosaminyl muramyl dipeptide (GMDP) has been augmented the antitumor action of chemotherapy drug cisplatin and tumor necrosis factor-alpha (TNFalpha) on the Ehrlich ascites carcinoma and melanoma B-16 mouse tumor models. The dose
Autor:
Olga A. Dmitrenko, Eugene V. Grishin, R. L. Komaleva, Natalia S. Shoshina, M. A. Simonova, L. V. Samokhvalova, Tatiana I. Valyakina, E. E. Petrova
Publikováno v:
Analytical and bioanalytical chemistry. 406(25)
Detection of staphylococcal toxins presents a great interest for medical diagnostics. Screening of clinical samples for the presence of several types of staphylococcal toxins using traditional methods—biological tests on animals or cell cultures as
Autor:
Olga E. Lakhtina, E. E. Petrova, M. A. Simonova, R. L. Komaleva, Natalia S. Shoshina, Galina N Philipenko, Igor V Osipov, Evgeniy V Grishin, Evgeniy K Singov, L. V. Samokhvalova, Tatiana I. Valyakina
Publikováno v:
Analytical chemistry. 84(15)
xMAP technology was used for simultaneous identification of six protein toxins (staphylococcal enterotoxins A and B, cholera toxin, ricin, botulinum toxin A, and heat labile toxin of E. coli). Monoclonal antibody-conjugated xMAP microspheres and biot
Autor:
Victor N. Morozov, A. O. Shepelyakovskaya, Eugene V. Grishin, M. A. Simonova, Yuri M. Shlyapnikov, Fedor Brovko, Elena A. Shlyapnikova, R. L. Komaleva
Publikováno v:
Analytical chemistry. 84(13)
Rapid ultrasensitive detection of gastrointestinal pathogens presents a great interest for medical diagnostics and epidemiologic services. Though conventional immunochemical and polymerase chain reaction (PCR)-based methods are sensitive enough for m
Autor:
Yu. V. Vertiev, R. L. Komaleva, A. Yu. Rubina, E. E. Petrova, N. A. Kalinina, Natalia S. Shoshina, Olga E. Lakhtina, Ye. V. Grishin, T. I. Valyakina, L. V. Samokhvalova, M. A. Filippova
Publikováno v:
Bioorganicheskaia khimiia. 35(3)
Monoclonal antibodies to cholera toxin were obtained. They do not cross-react with the termolabile toxin (LT) of Escherichia coli, ricin, diphtherial toxin, staphylococcus enterotoxins of SEA, SEB, SEI, SEG, or the lethal factor and protective antige
Publikováno v:
Bulletin of experimental biology and medicine. 143(2)
We studied the effect of combined treatment with cisplatin, glucosaminylmuramyl dipeptide, and TNF-alpha on viability of MCF-7, U-937, B16, and L-929 tumor cells, Ehrlich ascites carcinoma cells, and normal cells (human peripheral blood lymphocytes,
Autor:
P. K. Ivanov, Eugene A. Makarov, R. L. Komaleva, Tatiana I. Valyakina, Sergey V. Khaidukov, M. A. Simonova, E. E. Petrova, Tatiana M. Andronova, V. A. Nesmeyanov, Dmitry Yu. Blokhin
Publikováno v:
International immunopharmacology. 6(9)
We have demonstrated that biologically active muramyl peptides, in particular, glucosaminylmuramyl dipeptide (GMDP), augmented in vitro cytotoxic activity of tumor necrosis factor-alpha (TNF-alpha) against murine fibrosarcoma L929 cells. The introduc
Autor:
B F, Semenov, N S, Zakharova, M V, Britsina, N U, Mertsalova, M N, Ozeretskovskaia, T I, Valiakina, R L, Komaleva, T M, Andronova, V A, Nesmeianov
Publikováno v:
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (6)
As shown in this work, the synthetic immunomodulator glucosaminylmuramyldipeptide (GMDP) can be included into acellular pertussis vaccine (APV). The optimal doses of GMDP, ranging from 0.001 to 0.0001 microg, have been found. These doses enhance the
Autor:
O. G. Shamborant, R. L. Komaleva, Alexander A Malakhov, T. I. Valyakina, Tatyana M. Andronova, E. E. Petrova, V. A. Nesmeyanov
Publikováno v:
FEBS letters. 426(3)
Flow cytometry was used to demonstrate that cultured human melanoma BRO cells expressed membrane-bound tumour necrosis factor-alpha (TNF-alpha) and were able to release TNF-alpha upon treatment with glucosaminylmuramyl dipeptide (GMDP). The released