Zobrazeno 1 - 10
of 55
pro vyhledávání: '"R L, Duncan"'
Publikováno v:
Journal of musculoskeletalneuronal interactions. 10(2)
This study aimed to understand the role of Cav1.3, one of the four L-type voltage sensitive calcium channels (VSCC) alpha(1) subunits, in the skeletal response to mechanical loading and intermittent PTH treatment. The Cav1.3 mRNA is expressed in oste
Autor:
F M, Pavalko, N X, Chen, C H, Turner, D B, Burr, S, Atkinson, Y F, Hsieh, J, Qiu, R L, Duncan
Publikováno v:
The American journal of physiology. 275(6 Pt 1)
Mechanical stimulation of bone induces new bone formation in vivo and increases the metabolic activity and gene expression of osteoblasts in culture. We investigated the role of the actin cytoskeleton and actin-membrane interactions in the transmissi
Autor:
R L, Duncan, K A, Akanbi
Publikováno v:
Seminars in nephrology. 18(2)
Calcium (Ca2+) channels are present in non-excitable as well as in excitable cells. In bone cells of the osteoblast lineage, Ca2+ channels play fundamental roles in cellular responses to external stimuli including both mechanical forces and hormonal
Publikováno v:
The American journal of physiology. 273(3 Pt 1)
We previously demonstrated electrophysiologically that 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] shifts the activation threshold of L-type Ca2+ channels in osteoblasts toward the resting potential and prolongs mean open time. Presently, we used single-c
Autor:
R L, Duncan
Publikováno v:
ASGSB bulletin : publication of the American Society for Gravitational and Space Biology. 8(2)
One physiologic consequence of extended periods of weightlessness is the rapid loss of bone mass associated with skeletal unloading. Conversely, mechanical loading has been shown to increase bone formation and stimulate osteoblastic function. The mec
Publikováno v:
Endocrinology. 116:1189-1194
A6 cells form typical tight epithelia when grown in culture on permeable supports and exhibit active Na+ transport [short circuit current (Isc)], which is stimulated by aldosterone and corticosterone. Previous studies demonstrated nuclear binding of
Publikováno v:
American Journal of Physiology-Renal Physiology. 255:F736-F748
This study tests the hypothesis, in A6 epithelia, that 1) corticosterone stimulates active Na+ transport (short-circuit current, Isc) by an additional receptor mechanism to the type I (mineralocorticoid) and type II (glucocorticoid) mechanisms shared
Publikováno v:
Infection and Immunity. 41:1269-1278
Human serum, human transferrin (TF), and the iron chelator 1,10-phenanthroline (OP) produce iron-reversible fungistatic activity which has been attributed to simple iron deprivation. In this study, the influence of the size of the inoculum on the inh
Autor:
R L Duncan, D C Morrison
Publikováno v:
The Journal of Immunology. 132:1416-1424
The fate of bacterial lipopolysaccharide (LPS) after the uptake of Escherichia coli by macrophages in vitro was studied. The LPS of the galactose epimerase-deficient E. coli J5 mutant was specifically radiolabeled with [3H]galactose by growing the or