Zobrazeno 1 - 10
of 60
pro vyhledávání: '"R L, Comis"'
Autor:
R. L. Comis
Publikováno v:
Annals of Oncology. 3:S63-S67
Summary Etoposide has been in clincial trials for over 2 decades. From the inception of these investigations, both the oral and intravenous routes have been employed. The oral route has been shown to be convenient, sage, and effective in The trials o
Autor:
R. L. Comis, David Goldstein, D. C. Tormey, M. Shiraki, Ernest C Borden, J. E. Harris, B. Cheuvart, D. L. Trump
Publikováno v:
American Journal of Clinical Oncology. 13:420-423
As part of the Eastern Cooperative Oncology Group program for the assessment of new drugs in sarcomas, a Phase II trial of carboplatin was performed in patients who had received no more than one prior chemotherapy regimen. A total of 50 patients rece
Autor:
R L, Comis, R S, Finley
Publikováno v:
Seminars in oncology. 26(6 Suppl 18)
In recent years significant advances have been made in the treatment of metastatic non-small cell lung cancer. These advances have been due to both the discovery of new, more active drugs and an enhanced understanding of the biology of the disease, w
Autor:
A, Kovatich, D M, Friedland, T, Druck, P, Hadaczek, K, Huebner, R L, Comis, W, Hauck, P A, McCue
Publikováno v:
Cancer. 83(6)
The origins of and interrelations between low grade and high grade neuroendocrine lung tumors, typical and atypical carcinoids, and small cell lung carcinoma (SCLC) have not been elucidated. Karyotypic and molecular genetic studies have demonstrated
Publikováno v:
Oncology (Williston Park, N.Y.). 12(1 Suppl 2)
Despite advances in the treatment of small-cell lung cancer during the 1970s, with the use of combination chemotherapy, and in the 1980s, with the combination of etoposide and cisplatin plus concurrent radiation therapy, treatment success seems to ha
Autor:
C J, Langer, W J, Curran, S M, Keller, R B, Catalano, S, Litwin, K B, Blankstein, N, Haas, S N, Campli, R L, Comis
Publikováno v:
The cancer journal from Scientific American. 2(2)
Patients with locally advanced, initially unresectable non-small cell lung cancer (NSCLC) have a median survival time of 9 to 11 months, a 2-year survival rate of 13%, and a long-term survival rate of 5% to 7% when treated with radical thoracic radia
Perioperative therapy of non-small cell lung cancer: a review of adjuvant and neoadjuvant approaches
Autor:
D M, Friedland, R L, Comis
Publikováno v:
Seminars in oncology. 22(6)
Autor:
C J, Langer, J C, Leighton, R L, Comis, P J, O'Dwyer, C A, McAleer, C A, Bonjo, P F, Engstrom, S, Litwin, S, Johnson, R F, Ozols
Publikováno v:
Seminars in oncology. 22(4 Suppl 9)
A phase II trial of combination paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ) and carboplatin included 54 chemotherapy-naive patients with advanced non-small cell lung cancer. Eligibility mandated Eastern Cooperative Oncology Group
Autor:
R L, Comis
Publikováno v:
Seminars in oncology. 21(5 Suppl 12)
Cisplatin is one of the most important anticancer drugs yet developed. It proved critical in the development of curative programs for testicular cancer and in life-prolonging regimens for such diseases as small cell lung cancer, ovarian cancer, and m
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 270(3)
Ethacrynic acid (EA) is an inhibitor of the glutathione S-transferases (GSTs), a family of detoxification enzymes the expression of which has been associated with resistance to several classes of anticancer drugs. We performed a two-way randomized cr