Výsledky vyhledávání

Effects of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent on the cardiovascular and central nervous systems

Autor: R L, Riley, G N, Mir, G S, Rowles, J W, Sperow, R L, Alioto, J, Yelnosky

Publikováno v: Arzneimittel-Forschung. 28(8a)

1-(2,6-Dimethylphenyl)-3-methylamidinourea hydrochloride (WHR-1142A, lidamidine hydrochloride) has been reported to be a potent antidiarrheal agent in laboratory animals. This study defines its effects on the cardiovascular and central nervous system

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f6cd1ff67860458027833331d19b330f
https://pubmed.ncbi.nlm.nih.gov/582537

Zobrazit plný text záznamu

Pharmacological properties of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent

Autor: G N, Mir, J W, Sperow, R L, Riley, R L, Alioto, G W, Nuss, B J, Chou, J, Yelnosky

Publikováno v: Arzneimittel-Forschung. 28(8a)

1-(2',6'-Dimethylphenyl)-3-amidinourea hydrochloride (WHR-1142A, lidamidine hydrochloride), a potent, unique antidiarrheal agent, was tested for other pharmacological properties. It inhibited gastric acid secretion in both 4-h and 22-h pylorus-ligate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::faf4260d4d2c0dba964e9d8403694f56
https://pubmed.ncbi.nlm.nih.gov/582538

Zobrazit plný text záznamu

In vivo antimotility and antidiarrheal activity of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent. Comparison with diphenoxylate and loperamide

Autor: G N, Mir, R L, Alioto, J W, Sperow, J R, Eash, J B, Krebs, J, Yelnosky

Publikováno v: Arzneimittel-Forschung. 28(8a)

1-(2,6-Dimethylphenyl)-3-methyl-amidinourea hydrochloride (WHR-1142A, lidamidine hydrochloride) was shown to have potent antimotility, antidiarrheal and intestinal antisecretory activity in mice, rats and dogs. Antimotility activity was demonstrated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::27e5d2b270c8ec19f2f4d4d96c5718cd
https://pubmed.ncbi.nlm.nih.gov/582536

Zobrazit plný text záznamu

Antimotility and antisecretory activity of some aryl substituted amidinoureas

Autor: G H, Douglas, J, Diamond, W L, Studt, G N, Mir, R L, Alioto, K, Auyang, B J, Burns, J, Cias, P R, Darkes, S A, Dodson, S, O'Connor, N J, Santora, C T, Tsuei, J J, Zalipsky, H K, Zimmerman

Publikováno v: Arzneimittel-Forschung. 28(8a)

A number of aryl substituted amidinoureas have been prepared and examined for their gastrointestinal spasmolytic, antimotility, antidiarrheal and antisecretory effects. In general, antisecretory and antimotility effects have been found to be associat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8139cbbaa307f6305735516f67be5e4d
https://pubmed.ncbi.nlm.nih.gov/582534

Zobrazit plný text záznamu

ChemInform Abstract: ANTIMOTILITY AND ANTISECRETORY ACTIVITY OF SOME ARYL SUBSTITUTED AMIDINOUREAS

Autor: J. Diamond, W. L. Studt, H. K. Zimmermann, R. L. Alioto, S. A. Dodson, S. O'connor, K. Auyang, J. Cias, B. J. Burns, N. J. Santora, C. T. Tsuei, G. H. Douglas, P. R. Darkes, J. J. Zalipsky, G. N. Mir

Publikováno v: Chemischer Informationsdienst. 10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::264256fc547ae2a5efcf26d776f67c36
https://doi.org/10.1002/chin.197901183

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání