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Autor:
Volker Diehl, M. Kornacker, R Kurt Thomas, Thomas Zander, Jörn Bullerdiek, Nadia Massoudi, Christa Fonatsch, Juergen Wolf, Andrea Staratschek-Jox
Publikováno v:
British Journal of Cancer
Hodgkin-Reed Sternberg cells are derived from germinal centre B-cells in most cases. Somatic mutations affecting their rearranged immunoglobulin genes were detected, rendering potential functional rearrangements non-functional. Under physiological co