Zobrazeno 1 - 10
of 77
pro vyhledávání: '"R Kramp"'
Autor:
Hong Shik Yun, Tamalee R. Kramp, Kamalakannan Palanichamy, Philip J. Tofilon, Kevin Camphausen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Radiotherapy is the standard treatment for glioblastoma (GBM), but the overall survival rate for radiotherapy treated GBM patients is poor. The use of adjuvant and concomitant temozolomide (TMZ) improves the outcome; however, the effectivene
Externí odkaz:
https://doaj.org/article/a2cb9017ba34447e85204e2424d1bc93
Autor:
Kevin Camphausen, Philip J. Tofilon, Tamalee R. Kramp, Whoon Jong Kil, Jennifer Lee, Hong Shik Yun
AZD0530, a potent small-molecule inhibitor of the Src kinase family, is an anticancer drug used in the treatment of various cancers. In the case of glioblastoma (GBM), where resistance to radiotherapy frequently occurs, Src kinase is known as one of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c100aa664f94e962377d06729ea264b
https://doi.org/10.1158/1535-7163.c.6543204.v1
https://doi.org/10.1158/1535-7163.c.6543204.v1
Autor:
Agnes Ayme-Southgate, Richard A. Philipp, Richard Southgate, Catherine R. Kramp, Erik E. Sotka
Publikováno v:
Journal of Molecular Evolution. 67:653-669
All striated muscles respond to stretch by a delayed increase in tension. This physiological response, known as stretch activation, is, however, predominantly found in vertebrate cardiac muscle and insect asynchronous flight muscles. Stretch activati
Autor:
Michelle A. Meierhoefer, Ebony J. Hilton, John D. Knight, Matthew J. Walters, Clyde R. Metz, Jarrett H. Vella, Catherine R. Kramp, S. Patrick Dunn, Charles F. Beam, and Donald G. VanDerveer, Laela M. Hajiaghamohseni, Jason S. Overby, William T. Pennington, Bonnie J. Grant
Publikováno v:
Industrial & Engineering Chemistry Research. 46:8959-8967
The carbomethoxhydrazones of 1-tetralone, 6-methoxy-1-tetralone, and 5,7-dimethyl-1-tetralone were converted to dilithiated intermediates with excess lithium diisopropylamide and condensed with aromatic esters to give C-acylated intermediates that we
Autor:
N. Dwight Camper, Clyde R. Metz, Don VanDerveer, Carolyn L. Sober, Catherine R. Kramp, Stephen S. Jones, Michelle A. Meierhoefer, Bonnie J. Grant, John D. Knight, William T. Pennington, Jarrett H. Vella, Charles F. Beam
Publikováno v:
Journal of Heterocyclic Chemistry. 44:627-632
Several dilithiated C(α), O-oximes were prepared in excess lithium diisopropylamide-tetramethyl-ethylenediamine (LDA/TMEDA) and condensed with methyl 2-(aminosulfonyl)benzoate followed by acid cyclization of intermediates to spiro(benzoisothiazole-i
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 291:R977-R986
This study examined the role of intrarenal ANG II in the renal vascular reactivity changes occurring in the remaining kidney undergoing adaptation following contralateral nephrectomy. Renal blood flow responses to intrarenal injections of ANG II (0.2
Autor:
Jarrett H. Vella, Don VanDerveer, John D. Knight, Bonnie J. Grant, Nidhi S. Patel, Clyde R. Metz, Charles F. Beam, Carolyn L. Sober, William T. Pennington, Ebony J. Hilton, Catherine R. Kramp, Michelle A. Meierhoefer
Publikováno v:
Journal of Heterocyclic Chemistry. 43:315-319
Dilithiated 1-tetralone oxime was condensed with several electron enriched aromatic aldehydes, such as 4-methoxybenzaldehyde or lithiated 4-hydroxybenzaldehyde, followed by acid cyclization to new tetrahydronaphthisoxazoles, 3,3a,4,5-tetrahydronaphth
Autor:
R Kramp, Gérard Toubeau, Nadine Bouby, Nathalie Caron, Bruno Flamion, Denis Nonclercq, Jeannine Mertens, E Joly
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 32:241-248
1. The renin-angiotensin system may be involved in the compensatory adaptations occurring after the reduction of renal mass and during the consecutive changes leading to chronic renal failure. We therefore investigated the regulation of angiotensin I