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Peer review is believed to be important in maintaining the quality and integrity of research in academic endeavors. Recently, the value of the current peer review process, which is more than 100 years old has come into question. In the field of hemat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03addee7a98055cc9255bf8be702735
https://pubmed.ncbi.nlm.nih.gov/27159173

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Repertoire Analysis of CD8+ T Cell Responses to Minor Histocompatibility Antigens Involved in Graft-Versus-Host Disease

Autor: T M, Friedman, M, Gilbert, C, Briggs, R, Korngold

Publikováno v: The Journal of Immunology. 161:41-48

Graft-vs-host disease (GVHD) is a major complication of allogeneic bone marrow transplantation. Experimentally, lethal GVHD can be induced in MHC-matched strain combinations differing in expression of multiple minor histocompatibility Ags (miHA). Rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21b4cd90773a98f59dd108a945d9fac
https://doi.org/10.4049/jimmunol.161.1.41

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Anti-CD3 epsilon F(ab')2 fragments inhibit T cell expansion in vivo during graft-versus-host disease or the primary immune response to nominal antigen

Autor: B R Blazar, M K Jenkins, P A Taylor, J White, A Panoskaltsis-Mortari, R Korngold, D A Vallera

Publikováno v: The Journal of Immunology. 159:5821-5833

This study was undertaken to distinguish between several mechanisms responsible for graft-vs-host disease (GVHD) protection in anti-CD3epsilonF(ab')2 fragment (Fr)-treated recipients: TCR down-modulation, deletion, failure of expansion, or anergy ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff3fd7e13d1db0e1b00c0f718039aebe
https://doi.org/10.4049/jimmunol.159.12.5821

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Immune Cell Involvement inAnti-c-mycDNA Prevention of Tumor Formation in a Mouse Model of Burkitt'S Lymphoma

Autor: R. Townsend, R. Korngold, H. Hayasaka, Eric Wickstrom, G. D. Gray

Publikováno v: Nucleosides and Nucleotides. 16:1727-1730

Prophylactic therapy with 5′-dCACGTTGAGGGGCAT phosphorothioate, (2.5 nmol/hr) strongly inhibited tumorigenesis in Eμ-myc transgenic mice, and ablated spleen cell MYC antigen. However, the anti-c-myc DNA also stimulated proliferation of spleen cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::321be6864ba143ce9ea33e4f54a16bb2
https://doi.org/10.1080/07328319708006264

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Immunodominant CD4+ T cell receptor Vbeta repertoires involved in graft-versus-host disease responses to minor histocompatibility antigens

Autor: M A Berger, R Korngold

Publikováno v: The Journal of Immunology. 159:77-85

In vitro CTL responses to multiple minor histocompatibility Ags (miHA) are governed by immunodominance as demonstrated in the C57BL/6By (B6) anti-BALB.B strain combination. Immunodominance was also demonstrated to be operative in graft-vs-host diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::032c8c93aa700e79fcdaf6c57c1118c1
https://doi.org/10.4049/jimmunol.159.1.77

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