Zobrazeno 1 - 10
of 184
pro vyhledávání: '"R Koenen"'
Autor:
Rory R. Koenen
Publikováno v:
TH Open, Vol 08, Iss 02, Pp e175-e176 (2024)
Externí odkaz:
https://doaj.org/article/06f6096d5fe34dcf96ec3c094b449506
Autor:
Lucía Sanjurjo, Iris A. Schulkens, Pauline Touarin, Roy Heusschen, Ed Aanhane, Kitty C. M. Castricum, Tanja D. De Gruijl, Ulf J. Nilsson, Hakon Leffler, Arjan W. Griffioen, Latifa Elantak, Rory R. Koenen, Victor L. J. L. Thijssen
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Sanjurjo et al investigate the role of galectins in immunomodulation, reporting that chemokines can control galectin immunomodulatory function through a mechanism involving galectin-chemokine binding pairs. Specifically, the authors find that CXCL4 b
Externí odkaz:
https://doaj.org/article/c68df428db944ead902027a22af36904
Autor:
Laura. R. Koenen, Robert. J. Pawlik, Adriane Icenhour, Ljubov Petrakova, Katarina Forkmann, Nina Theysohn, Harald Engler, Sigrid Elsenbruch
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
In order to further understand mechanisms of pain-related expectations by classical conditioning, Koenen et al. carried out fMRI studies in healthy human participants using paradigms that either combined interoceptive visceral pain with somatic pain,
Externí odkaz:
https://doaj.org/article/2475eb403fc84e85b9d07882424ea0d9
Autor:
Alexandra C.A. Heinzmann, Daniëlle M. Coenen, Tanja Vajen, Judith M.E.M. Cosemans, Rory R. Koenen
Publikováno v:
TH Open, Vol 05, Iss 04, Pp e533-e542 (2021)
The cause of atherothrombosis is rupture or erosion of atherosclerotic lesions, leading to an increased risk of myocardial infarction or stroke. Here, platelet activation plays a major role, leading to the release of bioactive molecules, for example,
Externí odkaz:
https://doaj.org/article/037b5408509a4080840743629b8aea4b
Autor:
M. Christella L.G.D. Thomassen, Bryan R.C. Bouwens, Kanin Wichapong, Dennis P. Suylen, Freek G. Bouwman, Tilman M. Hackeng, Rory R. Koenen
Publikováno v:
Journal of Thrombosis and Haemostasis, 21, 1214-1226. Wiley
Background: Tissue factor pathway inhibitor (TFPI) is an important regulator of coagulation and a link between inflammation and thrombosis. During thrombotic events, TFPI is proteolytically inactivated by neutrophil elastase while bound to neutrophil
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1286 (2022)
Galectins, a family of glycan-binding proteins, are well-known for their role in shaping the immune microenvironment. They can directly affect the activity and survival of different immune cell subtypes. Recent evidence suggests that galectins also i
Externí odkaz:
https://doaj.org/article/d7b1885c133a4a57bc15a71661f72906
Autor:
Annemiek Dickhout, Pieter Van de Vijver, Nicole Bitsch, Stefan J. van Hoof, Stella L. G. D. Thomassen, Steffen Massberg, Peter Timmerman, Frank Verhaegen, Rory R. Koenen, Ingrid Dijkgraaf, Tilman M. Hackeng
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 829 (2022)
The efficacy of thrombolysis is inversely correlated with thrombus age. During early thrombogenesis, activated factor XIII (FXIIIa) cross-links α2-AP to fibrin to protect it from early lysis. This was exploited to develop an α2-AP-based imaging age
Externí odkaz:
https://doaj.org/article/3045194622e749f5ba69bba2da416819
Autor:
Maria Teresa Koenen, Elisa Fabiana Brandt, Dawid Marcin Kaczor, Tim Caspers, Alexandra Catharina Anna Heinzmann, Petra Fischer, Daniel Heinrichs, Theresa Hildegard Wirtz, Christian Trautwein, Rory R Koenen, Marie-Luise Berres
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 698 (2022)
Hepatic steatosis and chronic hepatocyte damage ultimately lead to liver fibrosis. Key pathophysiological steps are the activation and transdifferentiation of hepatic stellate cells. We assessed the interplay between hepatocytes and hepatic stellate
Externí odkaz:
https://doaj.org/article/4e8430abd24040baae0357b784214c65
Autor:
Annemiek Dickhout, Bibian M E Tullemans, Johan W M Heemskerk, Victor L J L Thijssen, Marijke J E Kuijpers, Rory R Koenen
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244736 (2021)
Galectin-1 (gal-1) is a carbohydrate-binding lectin with important functions in angiogenesis, immune response, hemostasis and inflammation. Comparable functions are exerted by platelet factor 4 (CXCL4), a chemokine stored in the α-granules of platel
Externí odkaz:
https://doaj.org/article/311672ba243c452db493f5a61210ee1d
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 580 (2022)
Platelet factor 4 (CXCL4) is a chemokine abundantly stored in platelets. Upon injury and during atherosclerosis, CXCL4 is transported through the vessel wall where it modulates the function of vascular smooth muscle cells (VSMCs) by affecting prolife
Externí odkaz:
https://doaj.org/article/028e94ab37584aa3a51c202163393d2b