Zobrazeno 1 - 10
of 5 831
pro vyhledávání: '"R Keith"'
Autor:
Harikrishnan Balachandran, Kyle Kroll, Karen Terry, Cordelia Manickam, Rhianna Jones, Griffin Woolley, Tammy Hayes, Amanda J Martinot, Ankur Sharma, Mark Lewis, Stephanie Jost, R Keith Reeves
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012439 (2024)
Natural killer (NK) cells play a critical role in virus control. However, it has remained largely unclear whether NK cell mobilization in SARS-CoV-2 infections is beneficial or pathologic. To address this deficit, we employed a validated experimental
Externí odkaz:
https://doaj.org/article/6060b7066f3a4926857118d4855db1c9
Autor:
Cordelia Manickam, Amit A Upadhyay, Griffin Woolley, Kyle W Kroll, Karen Terry, Courtney A Broedlow, Nichole R Klatt, Steven E Bosinger, R Keith Reeves
Publikováno v:
PLoS Pathogens, Vol 20, Iss 5, p e1012223 (2024)
Natural killer-like B (NKB) cells are unique innate immune cells expressing both natural killer (NK) and B cell receptors. As first responders to infection, they secrete IL-18 to induce a critical cascade of innate and adaptive immune cell infiltrati
Externí odkaz:
https://doaj.org/article/66bb7e6cf16643e8817768d7427341ee
Autor:
Sho Sugawara, Brady Hueber, Griffin Woolley, Karen Terry, Kyle Kroll, Cordelia Manickam, Daniel R Ram, Lishomwa C Ndhlovu, Paul Goepfert, Stephanie Jost, R Keith Reeves
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011629 (2023)
Despite their importance, natural killer (NK) cell responses are frequently dysfunctional during human immunodeficiency virus-1 (HIV-1) and simian immunodeficiency virus (SIV) infections, even irrespective of antiretroviral therapies, with poorly und
Externí odkaz:
https://doaj.org/article/d835155fe136473c8794b99be669f303
The pair production of Higgs bosons at the LHC can give information about the triple Higgs boson coupling. We perform an analytic one-loop calculation of the amplitudes for a pair of Higgs bosons in association with three partons, retaining the exact
Externí odkaz:
http://arxiv.org/abs/2408.12686
Autor:
Javier Antunez-Sanchez, Matthew Naish, Juan Sebastian Ramirez-Prado, Sho Ohno, Ying Huang, Alexander Dawson, Korawit Opassathian, Deborah Manza-Mianza, Federico Ariel, Cecile Raynaud, Anjar Wibowo, Josquin Daron, Minako Ueda, David Latrasse, R Keith Slotkin, Detlef Weigel, Moussa Benhamed, Jose Gutierrez-Marcos
Publikováno v:
eLife, Vol 9 (2020)
Histone modifications deposited by the Polycomb repressive complex 2 (PRC2) play a critical role in the control of growth, development, and adaptation to environmental fluctuations of most multicellular eukaryotes. The catalytic activity of PRC2 is c
Externí odkaz:
https://doaj.org/article/eb88ba5512b6471caa6e5b4af7d31487
Autor:
Yan Lai, Xueqing Maggie Lu, Josquin Daron, Songqin Pan, Jianqiang Wang, Wei Wang, Tokuji Tsuchiya, Eric Holub, John M McDowell, R Keith Slotkin, Karine G Le Roch, Thomas Eulgem
Publikováno v:
PLoS Genetics, Vol 16, Iss 9, p e1008993 (2020)
Plant NLR-type receptors serve as sensitive triggers of host immunity. Their expression has to be well-balanced, due to their interference with various cellular processes and dose-dependency of their defense-inducing activity. A genetic "arms race" w
Externí odkaz:
https://doaj.org/article/a9a59e0e26dd41babb906547dcb63b98
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008820 (2020)
The COVID-19 pandemic has caused more than 575,000 deaths worldwide as of mid-July 2020 and still continues globally unabated. Immune dysfunction and cytokine storm complicate the disease, which in turn leads to the question of whether stimulation or
Externí odkaz:
https://doaj.org/article/d87c6c283cb54556bcc06b00221bea17
Autor:
Cedar Warman, Kaushik Panda, Zuzana Vejlupkova, Sam Hokin, Erica Unger-Wallace, Rex A Cole, Antony M Chettoor, Duo Jiang, Erik Vollbrecht, Matthew M S Evans, R Keith Slotkin, John E Fowler
Publikováno v:
PLoS Genetics, Vol 16, Iss 4, p e1008462 (2020)
In flowering plants, gene expression in the haploid male gametophyte (pollen) is essential for sperm delivery and double fertilization. Pollen also undergoes dynamic epigenetic regulation of expression from transposable elements (TEs), but how this p
Externí odkaz:
https://doaj.org/article/a5248015d0fc4cf9b90e67d89127af8b
Autor:
Florian Jupe, Angeline C Rivkin, Todd P Michael, Mark Zander, S Timothy Motley, Justin P Sandoval, R Keith Slotkin, Huaming Chen, Rosa Castanon, Joseph R Nery, Joseph R Ecker
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007819 (2019)
The bacterium Agrobacterium tumefaciens has been the workhorse in plant genome engineering. Customized replacement of native tumor-inducing (Ti) plasmid elements enabled insertion of a sequence of interest called Transfer-DNA (T-DNA) into any plant g
Externí odkaz:
https://doaj.org/article/95ab8fb90c2041d8ab9f191a2f75b785