Výsledky vyhledávání

P380 Changes in faecal microbiome and metabolome are more pronounced in Crohn’s disease patients who adhered to the CD-TREAT diet and responded by calprotectin

Autor: V Svolos, R Hansen, R K Russell, D R Gaya, J P Seenan, J Macdonald, D Wilson, P Henderson, S Din, G T Ho, C Quince, U Z Ijaz, S Milling, B Nichols, R Papadopoulou, S McKirdy, L Gervais, S Shields, K Gerasimidis

Publikováno v: Journal of Crohn's and Colitis. 17:i513-i515

Background Treatment with the CD-TREAT solid food diet improves disease activity indices, faecal calprotectin (FCAL) levels and quality of life in adults and children with active Crohn’s disease (CD); particularly in patients who adhere to the diet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eab0b656c79bc9f17acb1d6efb9b9ef4
https://doi.org/10.1093/ecco-jcc/jjac190.0510

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DOP52 The faecal bacterial and fungal microbiome of newly-diagnosed, treatment naïve children with Crohn’s disease and the modifying effects of exclusive enteral nutrition and re-introduction of habitual diet

Autor: K Gerasimidis, B Nichols, R Papadopoulou, U Ijaz, R Rajendran, C Quince, R K Russell, R Hansen, G Ramage

Publikováno v: Journal of Crohn's and Colitis. 17:i122-i124

Background The fungal community (mycobiome) and immunological responses to specific fungi have been implicated in Crohn’s disease (CD) pathogenesis and its phenotype. There is limited data on profiling the mycobiome in paediatric CD and how it chan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3d14588f0239f121cad0935a7ec0063
https://doi.org/10.1093/ecco-jcc/jjac190.0092

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P774 Maintenance treatment with vedolizumab in children with Inflammatory Bowel Disease: follow-up results from the prospective multicenter VEDOKIDS study

Autor: O Atia, Z Shavit-Brunschwig, A Quteineh, R Lev-Tzion, R Stein, E Broide, D Urlep, J Hyams, M Aloi, D S Shouval, A Assa, S Hussey, J Markowitz, A Yerushalmy, E Miele, R K Russell, D Turner

Publikováno v: Journal of Crohn's and Colitis. 17:i904-i905

Background We previously reported the effectiveness of vedolizumab (VDZ) to induce remission in children with CD and UC enrolled in the prospective,multicenter VEDOKIDS study.In this extended analysis,we aimed to explore the effectiveness and safety

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c018d8b90dd0745f42a43e90943302d0
https://doi.org/10.1093/ecco-jcc/jjac190.0904

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P822 The negative impact of mental health comorbidity in children and young adults with inflammatory bowel disease: a UK population-based cohort study

Autor: R Cooney, K Barrett, R K Russell

Publikováno v: Journal of Crohn's and Colitis. 17:i956-i957

Background Whilst the high burden of mental health comorbidity in people with inflammatory bowel disease (IBD) is now being recognised, less is known about the additional impacts of having concurrent IBD and a mental health condition, especially in c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dcb3e760504814e39d8a8e58dd71a13b
https://doi.org/10.1093/ecco-jcc/jjac190.0952

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OP28 Children and young adults with inflammatory bowel disease have an increased incidence and risk of developing mental health conditions: a UK population-based cohort study

Autor: R Cooney, D Tang, K Barrett, R K Russell

Publikováno v: Journal of Crohn's and Colitis. 17:i39-i40

Background While it is widely recognised that inflammatory bowel disease (IBD) is associated with depression and anxiety, the burden of mental health conditions in children and young adults with IBD remains unclear. This study assessed this burden us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4473b35d8ef6d8b2647b71cf71d3dedb
https://doi.org/10.1093/ecco-jcc/jjac190.0028

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P804 Development and Validation of the Glasgow Exclusive Enteral Nutrition Index of Compliance (GENIE)

Autor: A Jatkowska, B White, B Nichols, V Svolos, K Gkikas, R Hansen, R K Russell, D Gaya, E Brownson, J P Seenan, S Milling, J MacDonald, K Gerasimidis

Publikováno v: Journal of Crohn's and Colitis. 17:i937-i938

Background Treatment adherence is key to the efficacy of exclusive enteral nutrition (100% EN) in active Crohn’s disease (CD), but there are currently no biomarkers to objectively support this. We explored faecal parameters as putative biomarkers o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::078f8e1db626f0e64c5f30d07c78b546
https://doi.org/10.1093/ecco-jcc/jjac190.0934

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DOP31 Gut metabolomic and compositional signatures predict response to treatment with exclusive enteral nutrition in children with active Crohn’s disease

Autor: K Gerasimidis, B Nichols, A Briola, J Havlik, A Mascellani, S Milling, U Ijaz, C Quince, V Svolos, R K Russell, R Hansen

Publikováno v: Journal of Crohn's and Colitis. 17:i96-i96

Background Predicting response to treatment with exclusive enteral nutrition (EEN) in paediatric Crohn’s disease (CD) can lead to more personalised, cost-effective, and efficacious therapy. We explored the ability of pre-treatment clinical and mult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::93e95d52e8e4b0e429a1681f0bd0cd73
https://doi.org/10.1093/ecco-jcc/jjac190.0071

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OP05 Outcome of induction therapy with vedolizumab in children: Results from the prospective, multi-centre VEDOKIDS study

Autor: Z Shavit, R Stein, M Aloi, O Ledder, G Focht, D Urlep, J Hyams, E Broide, B Vais, J Levine, D Shouval, M Matar, A Assa, J Rosh, S Hussey, J Markowitz, A Yerushalmy-Feler, E Miele, R Shaoul, R K Russell, D Turner

Publikováno v: Journal of Crohn's and Colitis. 16:i005-i006

Background Limited data are available on the use of Vedolizumab (VDZ) in paediatric Crohn’s Disease (CD) and Ulcerative Colitis (UC). We evaluated the effectiveness and safety of VDZ to induce remission at week 14 in the prospective, multicenter VE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5cafb6fe58567d416fb0f1db81195fe5
https://doi.org/10.1093/ecco-jcc/jjab232.004

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P308 Quadruple oral antibiotic treatment in refractory Paediatric Inflammatory Bowel Disease – incidence and analysis of responders from a, 10 year cohort

Autor: J J Meredith, K Armstrong, R K Russell, P Henderson, D C Wilson

Publikováno v: Journal of Crohn's and Colitis. 16:i334-i335

Background Recent, albeit limited, studies indicate that combination oral antibiotic therapy may be an efficacious, immunosuppressive-free, alternative strategy to achieve remission in a subset of medically refractory IBD patients. We sought to ident

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b8de9bb63ae7deae421c708b78e0630b
https://doi.org/10.1093/ecco-jcc/jjab232.435

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P705 The effects of commonly consumed dietary fibres on the gut microbiome and its fibre fermentative capacity in adults with inflammatory bowel disease in remission

Autor: K Gerasimidis, B Nichols, M McGowan, V Svolos, R Papadopoulou, M Kokkorou, M Rebull, T Bello Gonzalez, R Hansen, R K Russell, D R Gaya

Publikováno v: Journal of Crohn's and Colitis. 16:i602-i602

Background It has been suggested that the gut microbiome of patients with inflammatory bowel disease (IBD) is unable to ferment dietary fibre. This project explored the in vitro effect of fibre fermentation on production of short chain fatty acids (S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::392351ea0e66af91b44a5c47b49fa663
https://doi.org/10.1093/ecco-jcc/jjab232.826

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