Zobrazeno 1 - 7
of 7
pro vyhledávání: '"R K, McBride"'
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 264:L165-L174
To understand the influence of oxidant stress on the barrier function of airway epithelium, we conducted studies to determine the effects of chemically generated reactive oxygen species on permeability, permselectivity, and active ion transport of fe
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 262:L694-L698
The purpose of this study was to determine if arachidonic acid could alter ferret tracheal gland secretory responsiveness to a cholinergic agonist. We prepared glandular explants and incubated the explants in medium containing [3H]glucosamine. Secret
Publikováno v:
Environmental Research. 55:79-90
Oxidant air pollutants exacerbate several pulmonary diseases. Inhalation of ozone has been shown to induce airway smooth muscle hyperresponsiveness. Oxidant injury could also affect airway secretory mechanisms. We postulated that oxidant exposure wou
Publikováno v:
Fundamental and Applied Toxicology. 16:24-30
The purpose of this study was to examine the effect of the anticholinesterase agent, soman, on macromolecular secretion by ferret trachea, in vitro. We mounted pieces of ferret trachea in Ussing-type chambers. Secreted sulfated macromolecules were ra
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 16(1)
The purpose of this study was to examine the effect of the anticholinesterase agent, soman, on macromolecular secretion by ferret trachea, in vitro. We mounted pieces of ferret trachea in Ussing-type chambers. Secreted sulfated macromolecules were ra
Publikováno v:
The American journal of physiology. 259(4 Pt 1)
The purpose of the present study was to begin to characterize, pharmacologically, the alpha-adrenergic regulation of glycoconjugate secretion from airway glands. Using isolated gland cells from cat trachea, we determined the binding characteristics o
Publikováno v:
Journal of Applied Physiology. 66:1390-1396
The purpose of this study was to examine the role of acetylcholinesterase on mucociliary transport by use of a potent anticholinesterase agent, soman, and potential antagonists, atropine (muscarinic antagonist) and pralidoxime (acetylcholinesterase r