Zobrazeno 1 - 10
of 29
pro vyhledávání: '"R K, Kutty"'
Publikováno v:
Biochemical and Biophysical Research Communications. 215:386-393
Human retinal pigment epithelial (RPE) cells in culture respond to a mixture of cytokines (IFN-gamma, IL-1 beta, TNF-alpha) by producing large amounts of nitric oxide. Transforming growth factor-beta, unlike other growth factors, was found to inhibit
Autor:
S Shivaram, Gerald J. Chader, G Kutty, R K Kutty, D T Organisciak, B Wiggert, Paul Wong, R M Darrow, R T Fletcher
Publikováno v:
Biochemistry and Cell Biology. 72:499-503
Prolonged periods of high-intensity visible light exposure lead to photoreceptor cell degeneration, but the mechanism of damage is not understood. Increased clusterin mRNA levels have been found in several models of apoptosis, as well as in neurodege
Publikováno v:
Current Eye Research. 13:739-742
Transcription of heat shock genes takes place in response to the exposure of cells to elevated temperatures or other stress conditions. Heat shock transcription factor (HSF) plays an important role in the activation of such transcription. We report h
Publikováno v:
Investigative ophthalmologyvisual science. 42(6)
Heme oxygenase (HO)-1 immunoreactivity (IR) was examined in normal untreated retina and in retinal explants after in vitro treatment with stress agents.Enucleated eyes from young adult C3H mice were immediately fixed and cryosectioned and the retina
Publikováno v:
Investigative ophthalmologyvisual science. 41(12)
To determine the relative susceptibility of rats to retinal light damage at different times of the day or night.Rats maintained in a dim cyclic light or dark environment were exposed to a single dose of intense green light beginning at various times.
Publikováno v:
Investigative ophthalmologyvisual science. 39(7)
To determine the effects of age and long-term light- or dark-rearing environments on acute, intense-light-mediated retinal degeneration.Male albino rats were maintained in a dim cyclic light environment or in darkness for as long as 1 year. When aged
Autor:
R K, Kutty, G, Kutty, R, Kambadur, T, Duncan, E V, Koonin, I R, Rodriguez, W F, Odenwald, B, Wiggert
Publikováno v:
The Journal of biological chemistry. 271(34)
A detailed understanding of the mechanism of lipid transport in insects has been hampered by the inability to identify the proapolipophorin gene that encodes apolipophorins I and II, the principal protein components of lipophorin, the lipid transport
Publikováno v:
Investigative ophthalmologyvisual science. 36(11)
To determine the mechanism of photoreceptor cell death in the vitiligo mouse, a model of retinal degeneration in which the genetic defect is not retina specific but is instead caused by single point mutation in the microphthalmia (mi) gene that codes
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 92(4)
The effect of intense visible light (light damage) on the expression of heme oxygenase 1 (HO-1), a protein induced by oxidative stress, was investigated in the rat retina. A sensitive reverse transcription-PCR assay demonstrated the expression of mRN
Publikováno v:
Molecular and chemical neuropathology. 24(2-3)