Zobrazeno 1 - 10
of 11
pro vyhledávání: '"R K, Chowdhary"'
Publikováno v:
Photochemistry and Photobiology. 77:299-303
This study investigates the potential of Pluronics for the formulation of tetrapyrrole-based photosensitizers, with a particular focus on B-ring benzoporphyrin derivatives. The B-ring derivatives have a high tendency to aggregate in aqueous solutions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e79b3245ed3b185fdd82fabda38b49
https://doi.org/10.1562/0031-8655(2003)0770299fobdip2.0.co2
https://doi.org/10.1562/0031-8655(2003)0770299fobdip2.0.co2
Autor:
Ethan Sternberg, D Delmarre, David Dolphin, Noboru Hioka, R. K. Chowdhary, Namrata Chansarkar
Publikováno v:
Canadian Journal of Chemistry. 80:1321-1326
The synthetic route for the benzoporphyrin derivatives produces two regioisomers in equimolar quantities (ring A and B isomers). A derivative of the A-ring product, BPD-MA (benzoporphyrin-derivative monoacid ring A, verteporfin), has recently been ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10349ff9f9c00c5a82f7a21d4aef8e7c
https://doi.org/10.1139/v02-167
https://doi.org/10.1139/v02-167
Publikováno v:
Biopharmaceutics & Drug Disposition. 19:395-400
Photodynamic therapy (PDT) using the photosensitizer BPD-Verteporfin (liposomal benzoporphyrin derivative-monoacid ring A) has been shown in previous studies to be effective in the amelioration of inflammatory arthritis in both the MRL-lpr mouse and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a47f0485bbc75d452610a6f3e8eeda2
https://doi.org/10.1002/(sici)1099-081x(199809)19:6<395::aid-bdd117>3.0.co
https://doi.org/10.1002/(sici)1099-081x(199809)19:6<395::aid-bdd117>3.0.co
Autor:
R K Chowdhary, Modestus Obochi, J G Levy, Anna M. Richter, J D Waterfield, Herma C. Neyndorff, Leslie G. Ratkay
Publikováno v:
Clinical Immunology and Immunopathology. 72:255-263
The use of transcutaneous photodynamic therapy (PDT) has been investigated in the prevention of adjuvant enhanced arthritis in MRL/lpr mice. Mice receiving adjuvant were treated with PDT at 10-day intervals starting on the day of adjuvant administrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04f0572fef064a77ed25b2748f39492
https://doi.org/10.1006/clin.1994.1139
https://doi.org/10.1006/clin.1994.1139
Publikováno v:
Clinical and Experimental Immunology. 95:373-377
SUMMARY Although numerous experimentat immunomodulalory regimens have been reported to be effective in the treatment of rheumatoid arthritis, they also produce undesirable side effects. An alternative specific modality of localized treatment is photo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1cc648cc7d42be1c2a3283b8fb9b5c6
https://doi.org/10.1111/j.1365-2249.1994.tb07006.x
https://doi.org/10.1111/j.1365-2249.1994.tb07006.x
Publikováno v:
Biopharmaceuticsdrug disposition. 19(6)
Photodynamic therapy (PDT) using the photosensitizer BPD-Verteporfin (liposomal benzoporphyrin derivative-monoacid ring A) has been shown in previous studies to be effective in the amelioration of inflammatory arthritis in both the MRL-lpr mouse and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd1d7f77dc8ec9410327829c84dacfd4
https://pubmed.ncbi.nlm.nih.gov/9737820
https://pubmed.ncbi.nlm.nih.gov/9737820
Autor:
L G, Ratkay, R K, Chowdhary, A, Iamaroon, A M, Richter, H C, Neyndorff, E C, Keystone, J D, Waterfield, J G, Levy
Publikováno v:
Arthritis and rheumatism. 41(3)
To study the efficacy and mechanism of local transdermal photodynamic therapy (tPDT) in rabbits with antigen-induced arthritis (AIA).AIA in rabbits on day 14 postinduction was treated with an intravenous injection of benzoporphyrin-derivative monoaci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c53a88c2fafddc109c980b77aeec5e9
https://pubmed.ncbi.nlm.nih.gov/9506581
https://pubmed.ncbi.nlm.nih.gov/9506581
Autor:
Modestus Obochi, Agnes H. Chan, Douglas Waterfield, Leslie G. Ratkay, David W. C. Hunt, R. K. Chowdhary, Simon Leong, Julia G. Levy
Publikováno v:
Proceedings of SPIE.
The photosensitizer benzoporphyrin derivative monoacid ring A (VerteporfinR or BPD) has maximum absorption characteristics (690 nm) and biodistribution characteristics which permit activation of the drug in capillaries of the skin without causing ski
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbcfd20e89a24d35efc37aca2c29140e
https://doi.org/10.1117/12.199139
https://doi.org/10.1117/12.199139
Publikováno v:
SPIE Proceedings.
Photodynamic therapy (PDT) using benzoporphyrin derivative, monoacid ring A (BPD), and transdermal light was able to significantly treat symptoms of adjuvant-enhanced arthritis in MRL-lpr mice. Clinical and histological evaluation showed that PDT was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9907d3305bb876f718575679b22c484b
https://doi.org/10.1117/12.203424
https://doi.org/10.1117/12.203424
Autor:
R. K. Chowdhary, Meadows Howard E, Alice J. Canaan, Douglas Waterfield, Anna M. Richter, Julia G. Levy, Ashok K. Jain, Leslie G. Ratkay, Modestus Obochi
Publikováno v:
SPIE Proceedings.
Benzoporphyrin derivative monoacid ring A (BPD) is taken up rapidly (within 30 minutes) by most cells. Rapidly dividing tumor cell lines and mitogen activated murine T lymphocytes were found to take up significantly more (5 - 10 fold) BPD than do nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4864c134f2c38a89d3c5beeb7812ea6
https://doi.org/10.1117/12.168666
https://doi.org/10.1117/12.168666