Zobrazeno 1 - 10
of 29
pro vyhledávání: '"R K, Alpaugh"'
Autor:
Ashvathi Raghavakaimal, Massimo Cristofanilli, Cha-Mei Tang, R. K. Alpaugh, Kirby P. Gardner, Saranya Chumsri, Daniel L. Adams
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-12 (2022)
Abstract Background CCR5 is a motility chemokine receptor implicated in tumor progression, whose activation and subsequent endocytosis may identify highly aggressive breast cancer cell subtypes likely to spread into the circulatory system. Methods Th
Externí odkaz:
https://doaj.org/article/94fb5aec576d4dde891dae15d8d153b8
Autor:
Ashvathi Raghavakaimal, Massimo Cristofanilli, Cha-Mei Tang, R. K. Alpaugh, Kirby P. Gardner, Saranya Chumsri, Daniel L. Adams
Publikováno v:
Breast cancer research : BCR. 24(1)
Background CCR5 is a motility chemokine receptor implicated in tumor progression, whose activation and subsequent endocytosis may identify highly aggressive breast cancer cell subtypes likely to spread into the circulatory system. Methods The MDA-MB-
Autor:
Daniel C. Danila, R. K. Alpaugh, Cha-Mei Tang, Daniel J Gironda, Raymond Bergan, Daniel L. Adams, Thai H. Ho, Tuan L. Chuang, Brenda Hurtado
Publikováno v:
Cancer Research. 81:357-357
Background: Prostate cancers (PC) are intrinsically complex, with few prognostic biomarkers that differentiate aggressive and indolent disease. Cancer associated macrophage like cells (CAMLs) have shown to be significant independent prognostic indica
Autor:
Eliezer M. Van Allen, Eduoard Trabulsi, Philip Abbosh, Costas D. Lallas, Uttam Satyal, Alexander Kutikov, Michael Slifker, Kent W. Mouw, Paul Cairns, David Liu, Ilsiya Ibragimova, Elizabeth R. Plimack, Jean H. Hoffman-Censits, R. K. Alpaugh
Publikováno v:
Cancer Research. 81:548-548
Introduction: Neoadjuvant chemotherapy results in 30-40% complete response rates in patients undergoing radical cystectomy (RC) for bladder cancer. There is significant interest in identifying complete responders prior to RC in order to potentially a
Autor:
R. K. Alpaugh, Massimo Cristofanilli, Saranya Chumsri, William V. Williams, Markus D. Lacher, Daniel L. Adams, Cha-Mei Tang, Rena G. Lapidus, Stuart S. Martin
Publikováno v:
Cancer Research. 80:P5-06
Background: Tumor-associated macrophages have been shown to play a critical role in metastasis, angiogenesis, and immune escape. Cancer associated macrophage-like cells (CAMLs) are circulating stromal cell with macrophage expression subtypes, detecte
Autor:
Kerry S. Campbell, Alexander W. MacFarlane, R K. Alpaugh, Zoran Gatalica, David Liu, Joanne Xiu, Philip Abbosh, Alexander Kutikov, Rashida Ginwala, Elizabeth R. Plimack, Wolfgang Michael Korn, Eliezer M. Van Allen
Publikováno v:
Cancer Research. 80:6624-6624
Background: Neoadjuvant chemotherapy followed by radical cystectomy is the optimal treatment for patients with muscle invasive bladder cancer. Between 30 and 40% of patients receiving neoadjuvant chemotherapy will have pathological complete response
Autor:
Sandra V. Fernandez, Michelle Nahas, Phillip J. Stephens, Doron Lipson, Jie He, Gary A. Palmer, Lucy Aburto, R. K. Alpaugh, Massimo Cristofanilli, Geoff Otto
Publikováno v:
Cancer Research. 73:P6-12
Introduction: Inflammatory breast cancer (IBC) is a very aggressive variant of breast cancer with a poor prognosis.. Mouse Mammary Tumor-associated Virus (MMTV) and other infectious agents have been considered as possible etiological agents of IBC pa
Autor:
H Liu, AZ Luo, Zaiming Ye, J Jin, Khoi Chu, Kimberly M. Boley, MC Wright, R. K. Alpaugh, Zhaomei Mu, Massimo Cristofanilli, Sandra V. Fernandez, Fredika M. Robertson
Publikováno v:
Cancer Research. 71:P2-05
Background: Inflammatory breast cancer (IBC) is the most metastatic variant of locally advanced breast cancer. Although IBC is diagnosed less commonly than other types of breast cancer, it is extremely aggressive, and accounts for a disproportionate
Autor:
Tony McBryan, Naomi B. Haas, J. Zweibel, Peter D. Adams, Lainie P. Martin, Lisa Wang, Elaine McWhirter, Sebastien J. Hotte, R. K. Alpaugh, Amit M. Oza, R. Polintan, M. vonMehren, Samuel Litwin, I. Quirt
Publikováno v:
Investigational new drugs. 32(3)
Introduction Vorinostat is a small molecule inhibitor of class I and II histone deacetylases with preclinical activity in melanoma. Methods We evaluated 32 patients with advanced primary cutaneous or ocular melanoma in a multi-institutional setting (
Autor:
Michael B. Atkins, M. von Mehren, R. K. Alpaugh, I. Palazzo, Janice P. Dutcher, Lynn M. Schuchter, Louis M. Weiner, Joseph A. Sparano
Publikováno v:
Medical Oncology. 15:191-198
The inflammatory tumor lymphocytic infiltrates and spontaneous tumor regressions seen in patients with metastatic malignant melanomas suggest a cellular immune involvement. Enhancement of such responses has been the goal of R24 (GD3 ganglioside-speci