Zobrazeno 1 - 10
of 119
pro vyhledávání: '"R John, Simes"'
Autor:
Ian Campbell, Neil Wetzig, Owen Ung, David Espinoza, Gelareh Farshid, John Collins, James Kollias, Val Gebski, Rebecca Mister, R. John Simes, Martin R. Stockler, Grantley Gill
Publikováno v:
Breast, Vol 70, Iss , Pp 70-75 (2023)
Background: Sentinel node-based management (SNBM) is the international standard of care for early breast cancer that is clinically node-negative based on randomised trials comparing it with axillary lymph node dissection (ALND) and reporting similar
Externí odkaz:
https://doaj.org/article/fa7ad81456e94eaaa1bd8cf78eb82bac
Autor:
Andrzej S. Januszewski, David Chen, Russell S. Scott, Rachel L. O’Connell, Nanda R. Aryal, David R. Sullivan, Gerald F. Watts, Marja-Riitta Taskinen, Philip J. Barter, James D. Best, R. John Simes, Anthony C. Keech, Alicia J. Jenkins
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract People with diabetes are at risk of chronic complications and novel biomarkers, such as Advanced glycation end-products (AGEs) may help stratify this risk. We assessed whether plasma low-molecular weight AGEs, also known as LMW-fluorophores
Externí odkaz:
https://doaj.org/article/294b7a4d63544e699e028df0d5160f58
Autor:
Paul de Souza, Gary Hudes, Brian Egleston, Merryn Voysey, R. John Simes, Ian C. Marschner, Chee Khoon Lee
CCR Translation for This Article from Increase in Cholesterol Predicts Survival Advantage in Renal Cell Carcinoma Patients Treated with Temsirolimus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5b3eeed85d7d9e04d7e29aaaa73d23
https://doi.org/10.1158/1078-0432.22443918.v1
https://doi.org/10.1158/1078-0432.22443918.v1
Autor:
Paul de Souza, Gary Hudes, Brian Egleston, Merryn Voysey, R. John Simes, Ian C. Marschner, Chee Khoon Lee
Purpose: Temsirolimus is an effective treatment for renal cell carcinoma. It is associated with increases in serum cholesterol, triglyceride, and glucose. We investigated whether changes of these biomarkers could predict its efficacy.Experimental Des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b248ac02e32a86b432bdd75466623b
https://doi.org/10.1158/1078-0432.c.6520011
https://doi.org/10.1158/1078-0432.c.6520011
Autor:
Katrin M. Sjoquist, Andrew Martin, Nick Pavlakis, David Goldstein, Eric Tsobanis, Daniel Moses, Richard Maher, Wendy Hague, Val Gebski, Martin R. Stockler, R. John Simes
Publikováno v:
Journal of cancer research and clinical oncology.
Purpose Activity estimates should be accurately evaluated in phase 2 clinical trials to ensure appropriate decisions about proceeding to phase 3 trials. RECIST v1.1. progression-free survival (PFS) is a common endpoint in oncology; however, it can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9cfc4765b4dad31326766395090e6fd
https://pubmed.ncbi.nlm.nih.gov/36310299
https://pubmed.ncbi.nlm.nih.gov/36310299
Publikováno v:
The Medical journal of Australia. 217(10)
To investigate the frequency and legitimacy of substantive changes to the research plans of published randomised controlled trials (RCTs) undertaken in Australia.Comparison of methodology and analysis plans for RCTs specified in protocol documents (f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a52adb7df906f67588af46442110442
https://pubmed.ncbi.nlm.nih.gov/36353980
https://pubmed.ncbi.nlm.nih.gov/36353980
Autor:
Neena Modi, K. Cornthwaite, Kei Lui, Brian A Darlow, P. Koorts, Girish Deshpande, Rebecca L. Brown, Kristy P. Robledo, E. Noble, Margaret Broom, David Isaacs, Deborah Schofield, Tim Schindler, R. Tobiansky, D. Darcy, W. Nie, Ian C. Marschner, Mohamed E Abdel-Latif, P. Kwan, John Sinn, Anthony C Keech, Javeed Travadi, A. Lewis, A. Bhaskaracharya, Paolo Manzoni, Nicola C. Austin, Louise Goodchild, Kelly M. Dixon, Scott Morris, L. McKeown, E. Yeomans, Anu Kochar, Lisa M. Askie, C. Hua, Andrew J. Martin, William Tarnow-Mordi, David A Osborn, Clare L. Collins, Neil Marlow, Harshad Patel, David Espinoza, Wendy Hague, Patricia Graham, R. John Simes, Mohan Pammi, Mark Tracy, Melinda Cruz, B. Stenson, Margo Pritchard, Alpana Ghadge, Murray Hinder, Sacha Reid, Adrienne Gordon, Roger Soll, Helen G. Liley, Christopher J. D. McKinlay, Joanna Michalowski, R. Black, N Wilkes
Publikováno v:
The Lancet Child & Adolescent Health. 4:444-454
Summary Background Very low birthweight or preterm infants are at increased risk of adverse outcomes including sepsis, necrotising enterocolitis, and death. We assessed whether supplementing the enteral diet of very low-birthweight infants with lacto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061f1302fbdc4d1c15dee141a0049c42
https://doi.org/10.1016/s2352-4642(20)30093-6
https://doi.org/10.1016/s2352-4642(20)30093-6
Autor:
Malcolm West, Adrienne Kirby, Ralph A. Stewart, Stefan Blankenberg, David Sullivan, Harvey D. White, David Hunt, Ian Marschner, Edward Janus, Leonard Kritharides, Gerald F. Watts, John Simes, Andrew M. Tonkin, Neil Anderson, Ralph Stewart, Harvey White, Paul Nestel, Paul Glasziou, Marian Gandy, Jeannie Joughin, Jennifer Seabrook, Jenny Stephenson, Alison Clague, Stephen MacMahon, Philip Aylward, Malcolm Whiting, John McNeil, Andrew Tonkin, Craig Anderson, Jenny Baker, Elizabeth Barnes, Wendy Hague, Anthony Keech, Li‐Ping Li, Sarah Mulray, Helen Pater, Kristy Robledo, R. John Simes, Paul Magnus, John Shaw, Rory Collins, Andrew Thomson, Phillip Harris, Norman Sharpe, Paul Meier, Philip Barter, John Watson, Lawrence Beilin, Graeme Hankey, Michael Hobbs, Peter Thompson, Gerald Watts, David Colquhoun
Publikováno v:
Journal of the American Heart Association. 11(5)
Background Elevated plasma cystatin C levels reflect reduced renal function and increased cardiovascular risk. Less is known about whether the increased risk persists long‐term or is independent of renal function and other important biomarkers. Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7fcf1bf38d4590e84cde95bfcc0e788
https://pubmed.ncbi.nlm.nih.gov/35179040
https://pubmed.ncbi.nlm.nih.gov/35179040
Autor:
Rebecca Mercieca-Bebber, Renee Eggins, Kilian Brown, Val J. Gebski, Kate Brewer, Lenna Lai, Lisa Bailey, Michael J. Solomon, John W. Lumley, Peter Hewett, Andrew D. Clouston, Kate Wilson, Wendy Hague, Julian Hayes, Stephen White, Matt Morgan, R. John Simes, Andrew R. L. Stevenson
Publikováno v:
Annals of surgery.
To compare patient-reported urinary, bowel and sexual functioning of ALaCaRT Trial participants randomised to Open or Laparoscopic surgery for rectal cancer.The primary endpoint, non-inferiority of laparoscopic surgical resection adequacy, was not es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c7c96a2399428872fed0ce09da7933
https://pubmed.ncbi.nlm.nih.gov/35166265
https://pubmed.ncbi.nlm.nih.gov/35166265
Autor:
Rachel G. Woodford, Deborah D.‐X. Zhou, Peey‐Sei Kok, Sally J. Lord, Michael Friedlander, Ian C. Marschner, R. John Simes, Chee Khoon Lee
Publikováno v:
CancerReferences. 128(7)
Overall survival (OS) is the gold-standard end point for oncology trials. However, the availability of multiple therapeutic options after progression and crossover to receive investigational agents confound and delay OS data maturation. Progression-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcfd0e8c15ee0202e38e9e70bcc21f37
https://pubmed.ncbi.nlm.nih.gov/34985767
https://pubmed.ncbi.nlm.nih.gov/34985767